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The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. An integrin complex that comprises one alphaL subunit and one beta2 subunit. An integrin complex that comprises one alphaIIb subunit and one beta3 subunit. Located in the plasma membrane such that some covalently attached portion of the gene product, for example part of a peptide sequence or some other covalently attached moiety such as a GPI anchor, spans or is embedded in one or both leaflets of the membrane. An integrin complex that comprises one alphaM subunit and one beta2 subunit. An integrin complex that comprises one alphav subunit and one beta6 subunit. An integrin complex that comprises one alphav subunit and one beta8 subunit. An integrin complex that comprises one alphaX subunit and one beta2 subunit. An integrin complex that comprises one alpha4 subunit and one beta1 subunit. An integrin complex that comprises one alphaE subunit and one beta7 subunit. An integrin complex that comprises one alpha3 subunit and one beta1 subunit. An integrin complex that comprises one alphaD subunit and one beta2 subunit. An integrin complex that comprises one alpha4 subunit and one beta7 subunit. Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. An integrin complex that comprises one alpha2 subunit and one beta1 subunit. An integrin complex that comprises one alpha1 subunit and one beta1 subunit. A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands. An integrin complex that comprises one alpha5 subunit and one beta1 subunit. An integrin complex that comprises one alpha6 subunit and one beta1 subunit. An integrin complex that comprises one alpha6 subunit and one beta1 subunit. An integrin complex that comprises one alpha7 subunit and one beta1 subunit. An integrin complex that comprises one alpha8 subunit and one beta1 subunit. An integrin complex that comprises one alpha9 subunit and one beta1 subunit. Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. Any macromolecular complex composed of two or more polypeptide subunits, which may or may not be identical. Protein complexes may have other associated non-protein prosthetic groups, such as nucleotides, metal ions or other small molecules. An integrin complex that comprises one alpha10 subunit and one beta1 subunit. An integrin complex that comprises one alphav subunit and one beta1 subunit. An integrin complex that comprises one alpha11 subunit and one beta1 subunit. Penetrating at least one phospholipid bilayer of a plasma membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. An integrin complex that comprises one alphav subunit and one beta5 subunit. An integrin complex that comprises one alphav subunit and one beta3 subunit. Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: integrin complex
Acc: GO:0008305
Aspect: Cellular Component
Desc: A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
Synonyms:
  • laminin receptor protein
Proteins in PDR annotated with:
   This term: 98 [Search]
   Term or descendants: 99 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0008305 - integrin complex (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle