Protein Overview: arm-PD, arm-PA, ...

General Information:
Name(s) found:	FBpp0304835 [FlyBase] arm-PD / FBpp0089035 [FlyBase] arm-PA / FBpp0089034 [FlyBase] arm-PB / FBpp0089032 [FlyBase] arm-PE / FBpp0089031 [FlyBase]
Description(s) found: Found 73 descriptions. SHOW ALL	type=protein; loc=X:complement(1785863..1786152,1787436..1787532,1788541..1788813,1788874..1789074,1789147..1790786,1793013..1793043); ID=FBpp0304835; name=arm-PF; parent=FBgn0000117,FBtr0332583; dbxref=FlyBase:FBpp0304835,FlyBase_Annotation_IDs:CG11579-PF,REFSEQ:NP_001259149,GB_protein:AGB94995; MD5=2b2b00e5786a1e53f538f6974010c19b; length=843; release=r5.56; species=Dmel; [FlyBase] The gene armadillo is referred to in FlyBase by the symbol Dmel\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding. There is experimental evidence for 21 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 176 alleles are reported. The phenotypes of these alleles are annotated with 99 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene armadillo is referred to in FlyBase by the symbol Dmel\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding. There is experimental evidence for 21 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 176 alleles are reported. The phenotypes of these alleles are annotated with 99 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene armadillo is referred to in FlyBase by the symbol Dmel\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding. There is experimental evidence for 21 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 176 alleles are reported. The phenotypes of these alleles are annotated with 99 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] The gene armadillo is referred to in FlyBase by the symbol Dmel\arm (CG11579, FBgn0000117). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is X:1785434..1794673. It has the cytological map location 2B14. There is experimental evidence that it has the molecular function</span>: transcription activator activity; protein binding. There is experimental evidence for 21 unique biological process</span> terms, many of which group under: anatomical structure development; organ morphogenesis; cell adhesion; positive regulation of cellular biosynthetic process; regulation of developmental process; sensory organ development; positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; stem cell differentiation; reproductive process in a multicellular organism; delamination; cell junction organization. 176 alleles are reported. The phenotypes of these alleles are annotated with 99 unique terms, many of which group under: organ system; adult segment; abdominal ventral denticle belt; embryonic nervous system; female germline cyst; adult mesothoracic segment; embryonic/larval tracheal system; embryonic neuron; external compound sense organ; peripheral nervous system. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	843 amino acids
Gene Ontology:
Cellular Component:	apicolateral plasma membrane [TAS] nucleus [IPI] adherens junction [IDA][NAS][TAS] spot adherens junction [NAS] cytoplasm [IDA][NAS][TAS] zonula adherens [IDA][NAS][TAS] membrane [NAS] catenin complex [ISS][NAS] apical plasma membrane [IDA]
Biological Process:	dorsal closure [IMP][TAS] regulation of cell shape [IMP] ventral furrow formation [IMP] wing disc morphogenesis [IMP] protein localization [TAS] nervous system development [IMP] germ-line stem cell division [NAS] positive regulation of transcription [IMP] cell adhesion [IMP] cytoskeletal anchoring at plasma membrane [ISS] heart development [NAS][TAS] compound eye morphogenesis [IMP] ovarian follicle cell development [TAS] somatic stem cell maintenance [IMP] Wnt receptor signaling pathway [IMP][ISS][NAS][TAS] positive regulation of gene-specific transcription from RNA polymerase II promoter [IDA] neuroblast development [IMP] cuticle pattern formation [IMP] oocyte localization during germarium-derived egg chamber formation [TAS] cell-cell adhesion [IMP] delamination [IMP] cell morphogenesis [IMP] establishment or maintenance of cell polarity [NAS] imaginal disc-derived wing expansion [IMP] compound eye retinal cell programmed cell death [IMP] neuroblast fate determination [NAS] photoreceptor cell differentiation [IMP] oogenesis [IMP] positive regulation of JNK cascade [TAS] zonula adherens assembly [IMP][TAS] branch fusion, open tracheal system [IMP]
Molecular Function:	alpha-catenin binding [NAS] protein binding [IPI] transcription coactivator activity [IDA] transcription activator activity [IDA] cytoskeletal protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYMPAQNRT MSHNNQYNPP DLPPMVSAKE QTLMWQQNSY LGDSGIHSGA VTQVPSLSGK  60
   61 EDEEMEGDPL MFDLDTGFPQ NFTQDQVDDM NQQLSQTRSQ RVRAAMFPET LEEGIEIPST 120
  121 QFDPQQPTAV QRLSEPSQML KHAVVNLINY QDDAELATRA IPELIKLLND EDQVVVSQAA 180
  181 MMVHQLSKKE ASRHAIMNSP QMVAALVRAI SNSNDLESTK AAVGTLHNLS HHRQGLLAIF 240
  241 KSGGIPALVK LLSSPVESVL FYAITTLHNL LLHQDGSKMA VRLAGGLQKM VTLLQRNNVK 300
  301 FLAIVTDCLQ ILAYGNQESK LIILASGGPN ELVRIMRSYD YEKLLWTTSR VLKVLSVCSS 360
  361 NKPAIVDAGG MQALAMHLGN MSPRLVQNCL WTLRNLSDAA TKVEGLEALL QSLVQVLGST 420
  421 DVNVVTCAAG ILSNLTCNNQ RNKATVCQVG GVDALVRTII NAGDREEITE PAVCALRHLT 480
  481 SRHVDSELAQ NAVRLNYGLS VIVKLLHPPS RWPLIKAVIG LIRNLALCPA NHAPLREHGA 540
  541 IHHLVRLLMR AFQDTERQRS SIATTGSQQP SAYADGVRME EIVEGTVGAL HILARESHNR 600
  601 ALIRQQSVIP IFVRLLFNEI ENIQRVAAGV LCELAADKEG AEIIEQEGAT GPLTDLLHSR 660
  661 NEGVATYAAA VLFRMSEDKP QDYKKRLSIE LTNSLLREDN NIWANADLGM GPDLQDMLGP 720
  721 EEAYEGLYGQ GPPSVHSSHG GRAFHQQGYD TLPIDSMQGL EISSPVGGGG AGGAPGNGGA 780
  781 VGGASGGGGN IGAIPPSGAP TSPYSMDMDV GEIDAGALNF DLDAMPTPPN DNNNLAAWYD 840
  841 TDC

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..133]	PSI-BLAST	77.69897	Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
2	View Details	[134..689]	PSI-BLAST	93.522879	No description for 2gl7A was found.
3	View Details	[690..843]	PSI-BLAST	20.0	Importin beta

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: arm-PD, arm-PA, ...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: