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View Structure Prediction Details

Protein: arm-PD, arm-PA, ...
Organism: Drosophila melanogaster
Length: 843 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for arm-PD, arm-PA, ....

Description E-value Query
Range
Subject
Range
gi|125981023, gi... - gi|54642827|gb|EAL31571.1| GA11077-PA [Drosophila pseudoobscura], gi|125981023|ref|XP_001354518.1| G...
ARM_DROPS - Armadillo segment polarity protein OS=Drosophila pseudoobscura pseudoobscura GN=arm PE=3 SV=1
548.0 [0..4] [843..1]

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Predicted Domain #1
Region A:
Residues: [1-133]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYMPAQNRT MSHNNQYNPP DLPPMVSAKE QTLMWQQNSY LGDSGIHSGA VTQVPSLSGK  60
   61 EDEEMEGDPL MFDLDTGFPQ NFTQDQVDDM NQQLSQTRSQ RVRAAMFPET LEEGIEIPST 120
  121 QFDPQQPTAV QRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 77.69897
Match: 1wa5B
Description: Crystal structure of the exportin Cse1p complexed with its cargo ( Kap60p) and RanGTP
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [134-689]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SEPSQMLKHA VVNLINYQDD AELATRAIPE LIKLLNDEDQ VVVSQAAMMV HQLSKKEASR  60
   61 HAIMNSPQMV AALVRAISNS NDLESTKAAV GTLHNLSHHR QGLLAIFKSG GIPALVKLLS 120
  121 SPVESVLFYA ITTLHNLLLH QDGSKMAVRL AGGLQKMVTL LQRNNVKFLA IVTDCLQILA 180
  181 YGNQESKLII LASGGPNELV RIMRSYDYEK LLWTTSRVLK VLSVCSSNKP AIVDAGGMQA 240
  241 LAMHLGNMSP RLVQNCLWTL RNLSDAATKV EGLEALLQSL VQVLGSTDVN VVTCAAGILS 300
  301 NLTCNNQRNK ATVCQVGGVD ALVRTIINAG DREEITEPAV CALRHLTSRH VDSELAQNAV 360
  361 RLNYGLSVIV KLLHPPSRWP LIKAVIGLIR NLALCPANHA PLREHGAIHH LVRLLMRAFQ 420
  421 DTERQRSSIA TTGSQQPSAY ADGVRMEEIV EGTVGALHIL ARESHNRALI RQQSVIPIFV 480
  481 RLLFNEIENI QRVAAGVLCE LAADKEGAEI IEQEGATGPL TDLLHSRNEG VATYAAAVLF 540
  541 RMSEDKPQDY KKRLSI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 93.522879
Match: 2gl7A
Description: No description for 2gl7A was found.

Predicted functions:

Term Confidence Notes
binding 3.0667965351474 bayes_pls_golite062009
protein transporter activity 3.05338750264476 bayes_pls_golite062009
actin binding 2.8014924948341 bayes_pls_golite062009
protein binding 2.78733902345842 bayes_pls_golite062009
nucleic acid binding 2.74745843355294 bayes_pls_golite062009
cytoskeletal protein binding 2.61566088685247 bayes_pls_golite062009
transporter activity 2.48700774379895 bayes_pls_golite062009
I-SMAD binding 2.47815563591011 bayes_pls_golite062009
substrate-specific transporter activity 2.26725422172281 bayes_pls_golite062009
transcription regulator activity 2.16673352512615 bayes_pls_golite062009
RPTP-like protein binding 1.98880011077407 bayes_pls_golite062009
DNA binding 1.95242774903625 bayes_pls_golite062009
cell adhesion molecule binding 1.83254788740042 bayes_pls_golite062009
transcription activator activity 1.48948412083328 bayes_pls_golite062009
transmembrane transporter activity 1.28481004323799 bayes_pls_golite062009
transcription factor activity 1.20660383756339 bayes_pls_golite062009
protein transmembrane transporter activity 1.15447282085461 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.09652988954158 bayes_pls_golite062009
molecular transducer activity 1.05960420053443 bayes_pls_golite062009
signal transducer activity 1.05960420053443 bayes_pls_golite062009
steroid hormone receptor binding 0.979928797807954 bayes_pls_golite062009
nuclear localization sequence binding 0.611068932532731 bayes_pls_golite062009
hormone receptor binding 0.601092027102069 bayes_pls_golite062009
protein phosphatase binding 0.56816346673047 bayes_pls_golite062009
nuclear hormone receptor binding 0.550877840117317 bayes_pls_golite062009
androgen receptor binding 0.547783586885111 bayes_pls_golite062009
structural molecule activity 0.440301695287117 bayes_pls_golite062009
phosphatase binding 0.41064504734296 bayes_pls_golite062009
RNA binding 0.40024158562931 bayes_pls_golite062009
clathrin binding 0.35775052108553 bayes_pls_golite062009
profilin binding 0.282419977874124 bayes_pls_golite062009
signal sequence binding 0.27824906981293 bayes_pls_golite062009
active transmembrane transporter activity 0.252495966234234 bayes_pls_golite062009
ion transmembrane transporter activity 0.248585912061178 bayes_pls_golite062009
primary active transmembrane transporter activity 0.226380819487924 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 0.217517113570989 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 0.178770060806735 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 0.175241020572885 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 0.174922130116569 bayes_pls_golite062009
peptide binding 0.17066729499393 bayes_pls_golite062009
cadherin binding 0.1400783779596 bayes_pls_golite062009
nucleoside-triphosphatase activity 0.100181463251306 bayes_pls_golite062009
pyrophosphatase activity 0.0635404099346928 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.0548082069333885 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.052195223119721 bayes_pls_golite062009
cation transmembrane transporter activity 0.0405268469927988 bayes_pls_golite062009
transcription factor binding 0.0221966060394205 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [690-843]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELTNSLLRED NNIWANADLG MGPDLQDMLG PEEAYEGLYG QGPPSVHSSH GGRAFHQQGY  60
   61 DTLPIDSMQG LEISSPVGGG GAGGAPGNGG AVGGASGGGG NIGAIPPSGA PTSPYSMDMD 120
  121 VGEIDAGALN FDLDAMPTPP NDNNNLAAWY DTDC

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.0
Match: 1qgkA
Description: Importin beta
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle