General Information: |
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Name(s) found: |
FBpp0307743
[FlyBase]
Apc-PA / FBpp0084720 [FlyBase] |
Description(s) found:
SHOW ONLY BEST |
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Organism: | Drosophila melanogaster |
Length: | 2417 amino acids |
Gene Ontology: |
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Cellular Component: |
apical part of cell
[IDA]
cytoplasm [IDA] microtubule associated complex [ISS] axon [IDA] |
Biological Process: |
cell-cell adhesion
[IGI]
chitin-based larval cuticle pattern formation [IGI] head involution [IGI] axon guidance [IGI] brain development [IGI] imaginal disc pattern formation [IGI] microtubule-based process [ISS] neuroblast proliferation [IGI] medulla oblongata development [IGI] negative regulation of compound eye retinal cell programmed cell death [IMP] negative regulation of Wnt receptor signaling pathway [IGI] regulation of Wnt receptor signaling pathway [IGI] oocyte localization during germarium-derived egg chamber formation [IGI] |
Molecular Function: |
beta-catenin binding
[IDA]
microtubule binding [ISS] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MLEPTLTPDL EEGIAELSLE DVDVDSVPER KPHFLDYDAV PPPDYEEGFG ASSGEQLKMD 60 61 KKYERDGEVS DYELAASGYT KKEFTQDDNT LHFTQSAVGL GSGAVGKKPA AKHFLDENPI 120 121 PPDYMLAQEL REMREHRSLD RNFERQSAQQ QQLDELPPRN GGGSPASAGR PSRSKEPSYT 180 181 LSRFLDGDAP APAPRLPKGA AWTTSFDERY TSSAVEATLG SKVECVYSLL SMLGSNDPLE 240 241 MAKKFLELSG NAQSCATLRR SGCMPLLVQM MHAPDNDQEV RKCAGQALHN VVHSHPDEKA 300 301 GRREAKVLRL LDQIVDYCSF LKTLLQSGGE AIADDSDRHP LAAISSLMKV SFDEEHRHAM 360 361 CELGALHAIP NLVHLDHAVH GPKPEDQCCN SLRRYALMAL TNLTFGDENN KALLCGQKQF 420 421 MEALVAQLDS APDDLLQVTA SVLRNLSWRA DSNMKAVLNE IGTVTALALA AMRNRSENTL 480 481 KAILSALWNL SAHCSTNKAE FCAVDGALAF LVGMLSYEGP SKTLKIIENA GGILRNVSSH 540 541 IAVCEPYRQI LRQHNCLAIL LQQLKSESLT VVSNSCGTLW NLSARSAEDQ KFLWDNGAVP 600 601 MLRSLIHSKH AMISEGSSSA LKNLLNFRPA VQNHHQLDPI ARSMGLKALP TLEARKAKAL 660 661 QQELGERHTA ETCDNLDTGG KLDKERASSS SRRHPAPRLT RSAMLTKSES RDSVYSAKSD 720 721 CAYDHLIRSA SASDAHRKVK PKITDFDLEM EQDTEATEEQ PIDYSVKYSE NATKTSTYQE 780 781 TDLDQPTDFS LRYAENQIES DLDISGPAGG QKSTITPPAE TVPEKSEGQE ILLILDDSVK 840 841 CYQTEDTPYV ISNAASVTDL RVAAKADAEA EVKPEVREVT SKEGAPKKLP KLSQCGSGSY 900 901 TPEKPINYCE EGTPGYFSRY DSLSSLDESG KANQAIVGTD ADIKPKLEKQ EEQESQPAEQ 960 961 VLTKPPTQAN SALETPLMFS RRSSMDSLVH DPDVDVANCD DKSSVVSDFS RLASGVISPS1020 1021 EIPDSPTQSM PQSPRRNSVA GSGQNVDSPP VVIPASLQPL RSVFEDDLSS FNVEHTPAQF1080 1081 STATSLSNLS IVDDEKAPAS VAEEDNEDEL LLANCINMGM QRKPTEAVKS TVVNSEVDVA1140 1141 EETIRSYCTE DTPALLSKVP SNTNLSVISM SSTDPKDATA GQAQMYAHQL SDDVSSNASD1200 1201 CGGASGHLLQ QCIRDGMKKP LGEATSDPIA MLRRGGNELP GYLPSADEMN KFLVEDSPCN1260 1261 FSVVSGLSNL TVGSSLVGPA VQLKETEPSS ADQNPEMKAK PGKQEQVRRP PHWQDDSLSS1320 1321 LSIDSEDDTN LLSQAIAAGC NRPKSNLGFS SNGKRSSSLS SSQPIAINAA TSASSLNSAM1380 1381 TVRKSQQQES YSSVDSSDSN DNQSKSLFEL CILKGMYKTK EPGARAQQMQ EQPIVGSSSV1440 1441 QSNPSLKQFD SLPVQLPSSG QVKRQRHHHH HHHHRERERE RKDEKLLQEC INTGISKKIN1500 1501 AVPKNVLATS AAALEPCHPM AATTSASALS TAAPDVEQKA HATSNPQQQS STHPSSHILP1560 1561 NPIDAIATVT DTVRSPAAPN QGNGNASQNG LETATGSKDL DSEDRSSDES NQSFIMETMV1620 1621 RLDSALNETC ISGASEKHKD PDLMLKSVER LTMEFVTSAE QLRSSSHNHS SSNSHKNNSS1680 1681 NNTWNESTCP NDVSFPSVSQ TAPVLASLSL DEDATEARSL HELIEITPTN EQQPESLEGE1740 1741 TDTLVNGHAD SYSGSSGGLN FQLGGQVQNA GVRLEPQRLL FNGTSASIMT NSTMIAFEAR1800 1801 ALAENLLQPA ATDDDTTEMT FSLNSLDLDN IRPPSGMESL NSCYQDHSQP SSLRQAMPSK1860 1861 SPRFARKMFP ANLVARRALG HLAGSAESVN SSCNLLDNIK PPSLMDELLD SMISVDSIQS1920 1921 EVADGEQDCS MATTISVSNY ETAACDDQTM TVLQSCFDED EDATMNDYSS AESTPKHGST1980 1981 PSPNRRSLTP KDKRRLTKDR FKTYTIATSC EMEAPEANET LQIEIVEAAV PVATPSPRAN2040 2041 GRRRGSAERY KTQLIECPLA LIQPQPDDCP SEQLSSIRAM MQQFTFITDI NIGHSQETCE2100 2101 STDHPEDAGE SPECDQNSET ESCDGQEPDQ LPPPPSIVDL RTSVVKPTTL EPATAVKLVR2160 2161 GRKKPAYVSP YSMQSQRNSN NAAPSKKKTL SPTIAKRSLV PGGSGVRLPA KKKPTPPPEP2220 2221 APARLERQGT FVKDEPTNSN VQVPVVETKP AQTSPTHRAS KLPTKKGTAS GGSPSKAGSP2280 2281 KRIPLAPARR MTPQRANTSL RLAAGKSHAA SRVVSGRVSS TTPPSRSNSN LNGSSAAAAA2340 2341 AAKINHAQSR IANIWKRVDE AKTKQSSSNL RTQKTKSSNM LNANGTKPTL LRSSTFDNTP2400 2401 STAGGVKSKL PVVGARK |
SHOWING SINGLE HITS. [ Hide Single Hits ]
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Domains predicted:
# | Region(s) | Method | Confidence | Match Description | |
1 | View Details | [1..97] | N/A | No confident structure predictions are available. | |
2 | View Details | [98..160] | 14.69897 | Tumor suppressor gene product Apc | |
3 | View Details | [161..630] | 126.0 | beta-Catenin | |
4 | View Details | [631..684] | N/A | No confident structure predictions are available. | |
5 | View Details | [685..825] | N/A | No confident structure predictions are available. | |
6 | View Details | [826..955] | N/A | No confident structure predictions are available. | |
7 | View Details | [956..1083] | 2.45 | Beta-catenin in complex with a phosphorylated APC 20aa repeat fragment | |
8 | View Details | [1084..1281] | N/A | No confident structure predictions are available. | |
9 | View Details | [1282..1396] | 1.132988 | View MSA. No confident structure predictions are available. | |
10 | View Details | [1397..1589] | N/A | No confident structure predictions are available. | |
11 | View Details | [1590..1794] | N/A | No confident structure predictions are available. | |
12 | View Details | [1795..2030] | N/A | No confident structure predictions are available. | |
13 | View Details | [2031..2114] | N/A | No confident structure predictions are available. | |
14 | View Details | [2115..2236] | 1.128988 | View MSA. No confident structure predictions are available. | |
15 | View Details | [2237..2417] | 1.117985 | View MSA. No confident structure predictions are available. |
Functions predicted (by domain):
# | Gene Ontology predictions | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
2 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
3 |
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4 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
5 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
6 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
7 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
8 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
9 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
10 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
11 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
12 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
13 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
14 | No functions predicted. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
15 | No functions predicted. |
Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)