Protein Overview: PP2A-B'-PB

General Information:
Name(s) found:	PP2A-B'-PB / FBpp0082978 [FlyBase]
Description(s) found: Found 19 descriptions. SHOW ALL	The gene PP2A-B' is referred to in FlyBase by the symbol Dmel\PP2A-B' (CG7913, FBgn0042693). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13993451..14005771. It has the cytological map location 90F4-90F5. Based on sequence similarity, it is predicted to have molecular function</span>: protein phosphatase type 2A regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein amino acid dephosphorylation. 23 alleles are reported. The phenotype of these alleles is annotated with: salivary gland. It has 8 annotated transcripts and 8 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	984 amino acids
Gene Ontology:
Cellular Component:	protein phosphatase type 2A complex [IEA][ISS]
Biological Process:	neuromuscular junction development [IMP] anti-apoptosis [NAS] neuromuscular synaptic transmission [IMP] signal transduction [IEA] protein amino acid dephosphorylation [ISS]
Molecular Function:	protein phosphatase type 2A regulator activity [IEA][ISS][NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFGAMLLTG NGLKGPKQQQ QQHQQEPQQQ QQQSQQQQQE QKKPAPIKSS SKEQETQPIA  60
   61 AGYYALGIRI PKSPSFHSGL DQLADDELDD QVQDQQQEQQ QTGSRFRFSS VEELKAKFEG 120
  121 RKTPLSPPEA AAGGAAGSGA PTTSSSPSSS STSSNSSASA LSSLSQAASS SLASAAANSS 180
  181 ASSSAATYGG GANSAAAALI ASSPFGSQSS TSSLSLSSNA GMSKNAAGAG SGSGSGTTST 240
  241 GAASGSNSLV STLAQHFSAA TSAAASAAAA AASSASAASS SSASSSSTAT NNAASSSIAA 300
  301 SKSPVSAAAA IKNILNATKS VGTSAAAAAA AAATSSSSSP SSAAAVPSSA ATAVAAVPTT 360
  361 SDVPAEEMRP TVAQNLVGGI SISLGIGQRN GGAAPASSAV MVTPNATMVV TTSSLSIRQN 420
  421 GDILPGHPAG LQPSPQTLQQ LTGSPGRARD RNLFYTPPTA SVAMALPALR ETAASEREEL 480
  481 FIQKIQQCCT LFDFSEPLSD LKFKEVKRAA LHEMVDFLTN QNGVITEVIY PEAINMFAVN 540
  541 LFRTLPPSSN PNGAEFDPEE DEPTLESSWP HLQLVYELFL RFLESPDFQP SMAKRFIDHQ 600
  601 FVLQLLDLFD SEDPRERDFL KTVLHRIYGK FLGLRAFIRK QINNVFYRFI YETEHHNGIA 660
  661 ELLEILGSII NGFALPLKEE HKQFLLKVLL PLHKAKSLSV YHPQLTYCVV QFLEKDPSLS 720
  721 EAVIKSLLKF WPKTHSPKEV MFLNELEELL DVIEPAEFQK VMVPLFRQIA KCVSSPHFQV 780
  781 AERALYYWNN EYIMSLITDN SAVILPIMFP ALNRNSKTHW NKTIHGLIYN ALKLFMEIDQ 840
  841 RLFDECSKNY KQEKQMEREK LSQREELWQQ VESLAKTNPE WTKARRFNDC LPVSDSRALC 900
  901 DQYSENSDSA YDQSEQRARQ PPPPLPPQKQ AHQEPREIRG ERNKDKPLLR RKSDLPSDSG 960
  961 TVKALNEHKR TDEYLTTPPP DGNY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Searching the YRC Public Image Repository, found results:

Currently showing to of results.

[View Search in the YRC Public Image Repository]

Searching the YRC Public Image Repository, found no results.

Ginzu Version Information

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

Gene Ontology predictions

No functions predicted.

Term	Confidence	Notes
phosphoprotein phosphatase activity	7.41566231556356	bayes_pls_golite062009
phosphatase activity	6.2815295903206	bayes_pls_golite062009
protein serine/threonine phosphatase activity	6.23975872771765	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.04343158483355	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.13001603767079	bayes_pls_golite062009
protein phosphatase type 2A regulator activity	4.9046120881035	bayes_pls_golite062009
binding	3.0667965351474	bayes_pls_golite062009
phosphatase regulator activity	2.6399267580941	bayes_pls_golite062009
protein phosphatase regulator activity	2.60055057218296	bayes_pls_golite062009
protein binding	1.73688475473996	bayes_pls_golite062009
myosin phosphatase activity	1.2020405346133	bayes_pls_golite062009
nucleic acid binding	1.13208464017585	bayes_pls_golite062009
hydrolase activity	0.42501390959416	bayes_pls_golite062009
transcription regulator activity	0.385452858197632	bayes_pls_golite062009
protein kinase activity	0.321074115018386	bayes_pls_golite062009
DNA binding	0.309260217284589	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.176747874443749	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.0257259839107	bayes_pls_golite062009
kinase activity	0.0101018729931129	bayes_pls_golite062009

No functions predicted.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.44

Source: Reynolds et al. (2008)

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..209]	FFAS03	1.05	No description for 2j63A was found.
2	View Details	[210..377]	MSA	4.213994	View MSA. No confident structure predictions are available.
3	View Details	[378..439]	deduced	N/A	No confident structure predictions are available.
4	View Details	[440..883]	PSI-BLAST	1000.0	No description for 2nppB was found.
5	View Details	[884..984]	deduced	N/A	No confident structure predictions are available.

Protein Overview: PP2A-B'-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: