YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: PP2A-B'-PB
Organism: Drosophila melanogaster
Length: 984 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PP2A-B'-PB.

Description E-value Query
Range
Subject
Range
gi|45501158, gi|... - gi|50726892|ref|NP_998483.1| delta isoform of regulatory subunit B56, protein phosphatase 2A [Danio ...
946.0 [0..390] [980..14]

Back

Predicted Domain #1
Region A:
Residues: [1-209]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVFGAMLLTG NGLKGPKQQQ QQHQQEPQQQ QQQSQQQQQE QKKPAPIKSS SKEQETQPIA  60
   61 AGYYALGIRI PKSPSFHSGL DQLADDELDD QVQDQQQEQQ QTGSRFRFSS VEELKAKFEG 120
  121 RKTPLSPPEA AAGGAAGSGA PTTSSSPSSS STSSNSSASA LSSLSQAASS SLASAAANSS 180
  181 ASSSAATYGG GANSAAAALI ASSPFGSQS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 1.05
Match: 2j63A
Description: No description for 2j63A was found.

Predicted Domain #2
Region A:
Residues: [210-377]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSSLSLSSN AGMSKNAAGA GSGSGSGTTS TGAASGSNSL VSTLAQHFSA ATSAAASAAA  60
   61 AAASSASAAS SSSASSSSTA TNNAASSSIA ASKSPVSAAA AIKNILNATK SVGTSAAAAA 120
  121 AAAATSSSSS PSSAAAVPSS AATAVAAVPT TSDVPAEEMR PTVAQNLV

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [378-439]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGISISLGIG QRNGGAAPAS SAVMVTPNAT MVVTTSSLSI RQNGDILPGH PAGLQPSPQT  60
   61 LQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [440-883]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QLTGSPGRAR DRNLFYTPPT ASVAMALPAL RETAASEREE LFIQKIQQCC TLFDFSEPLS  60
   61 DLKFKEVKRA ALHEMVDFLT NQNGVITEVI YPEAINMFAV NLFRTLPPSS NPNGAEFDPE 120
  121 EDEPTLESSW PHLQLVYELF LRFLESPDFQ PSMAKRFIDH QFVLQLLDLF DSEDPRERDF 180
  181 LKTVLHRIYG KFLGLRAFIR KQINNVFYRF IYETEHHNGI AELLEILGSI INGFALPLKE 240
  241 EHKQFLLKVL LPLHKAKSLS VYHPQLTYCV VQFLEKDPSL SEAVIKSLLK FWPKTHSPKE 300
  301 VMFLNELEEL LDVIEPAEFQ KVMVPLFRQI AKCVSSPHFQ VAERALYYWN NEYIMSLITD 360
  361 NSAVILPIMF PALNRNSKTH WNKTIHGLIY NALKLFMEID QRLFDECSKN YKQEKQMERE 420
  421 KLSQREELWQ QVESLAKTNP EWTK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1000.0
Match: 2nppB
Description: No description for 2nppB was found.

Predicted functions:

Term Confidence Notes
phosphoprotein phosphatase activity 7.41566231556356 bayes_pls_golite062009
phosphatase activity 6.2815295903206 bayes_pls_golite062009
protein serine/threonine phosphatase activity 6.23975872771765 bayes_pls_golite062009
phosphoric ester hydrolase activity 6.04343158483355 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 5.13001603767079 bayes_pls_golite062009
protein phosphatase type 2A regulator activity 4.9046120881035 bayes_pls_golite062009
binding 3.0667965351474 bayes_pls_golite062009
phosphatase regulator activity 2.6399267580941 bayes_pls_golite062009
protein phosphatase regulator activity 2.60055057218296 bayes_pls_golite062009
protein binding 1.73688475473996 bayes_pls_golite062009
myosin phosphatase activity 1.2020405346133 bayes_pls_golite062009
nucleic acid binding 1.13208464017585 bayes_pls_golite062009
hydrolase activity 0.42501390959416 bayes_pls_golite062009
transcription regulator activity 0.385452858197632 bayes_pls_golite062009
protein kinase activity 0.321074115018386 bayes_pls_golite062009
DNA binding 0.309260217284589 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.176747874443749 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.0257259839107 bayes_pls_golite062009
kinase activity 0.0101018729931129 bayes_pls_golite062009

Predicted Domain #5
Region A:
Residues: [884-984]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARRFNDCLPV SDSRALCDQY SENSDSAYDQ SEQRARQPPP PLPPQKQAHQ EPREIRGERN  60
   61 KDKPLLRRKS DLPSDSGTVK ALNEHKRTDE YLTTPPPDGN Y

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle