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The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. The biological process by which a synapse between a motor neuron and a muscle is initially formed. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell). The developmental sequence of events leading to the formation of adult muscle that occurs in the anima. In vertebrate skeletal muscle the main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. The process whose specific outcome is the progression of the neuromuscular junction over time, from its formation to the mature structure. A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates. The accumulation of acetylcholine receptors (AChRs) in a narrow, central region of muscle fibers, in apposition to nerve terminals.

View Gene Ontology (GO) Term

GO TERM SUMMARY

Name: neuromuscular junction development
Acc: GO:0007528
Aspect: Biological Process
Desc: The process whose specific outcome is the progression of the neuromuscular junction over time, from its formation to the mature structure.
Proteins in PDR annotated with:
   This term: 107 [Search]
   Term or descendants: 185 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0007528 - neuromuscular junction development (interactive image map)

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