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Protein Overview: CG6194-PA

General Information:
Name(s) found: CG6194-PA / FBpp0082569 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6194 (CG6194, FBgn0038325). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11179433..11182641. It has the cytological map location 88F1. Based on sequence similarity, it is predicted to have molecular function</span>: cysteine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process</span>: autophagic cell death; salivary gland cell autophagic cell death. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 668 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: autophagy [ISS]
    autophagic cell death [IEP]
    proteolysis [ISS]
    salivary gland cell autophagic cell death [IEP]
    Molecular Function: cysteine-type endopeptidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNYDGLLSKL TDEKLMLFEA AGEGTIVEGS RICGQDADPL SLPLVEDGAI EEEQAAPIQT  60
   61 IHRTVFAVPR VPSPSPVSTS GANLNLKTEN AATATPQRKI STSSRFMNAF SQLYGGGNSG 120
  121 PSCGHVEQHN EEPGDLSANR TPTKGMESKL VAMWHNVKYG WSGKMRQTSF SKEQPVWLLG 180
  181 RCYHRRFTPP VSMESSITEL PSGADTTPDN ATSAFDSIQA TSTSTSLYPA LNPQQIDEIV 240
  241 VPQELGMDAV ENQVGEQPWE EGIEGFRRDF YSRIWMTYRR EFPIMNGSNY TSDCGWGCML 300
  301 RSGQMLFAQG LICHFLGRSW RYDSESQLHS TYEDNMHKKI VKWFGDSSSK SSPFSIHALV 360
  361 RLGEHLGKKP GDWYGPASVS YLLKHALEHA AQENADFDNI SVYVAKDCTI YLQDIEDQCS 420
  421 IPEPAPKPHV PWQQAKRPQA ETTKTEQQQH WKSLIVLIPL RLGSDKLNPV YAHCLKLLLS 480
  481 TEHCLGILGG KPKHSLYFVG FQEDRLIHLD PHYCQEMVDV NQENFSLHSF HCKSPRKLKA 540
  541 SKMDPSCCIG FYCATKSDFD NFMESVQLYL HPMRCASGAT VDKAAGSHHT TPQSSHQTEQ 600
  601 TEMNYPLFSF SRGRCMDHER DEMSDSLYKP LIKQVASLAQ ELGAQLAPPQ HGDEHDQDDS 660
  661 ESEEFVLL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..126] deduced N/A No confident structure predictions are available.
    2 View Details [127..193] MSA 1.034987 View MSA. No confident structure predictions are available.
    3 View Details [194..668] PSI-BLAST 147.0 Structure of human Atg4b

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • peptidase activity
    		•  4.90619850296986 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.64381885397949 bayes_pls_golite062009
  • endopeptidase activity
    		•  3.75054525912786 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  3.05412701733177 bayes_pls_golite062009
  • hydrolase activity
    		•  2.66167923792227 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.13397229861051 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  2.06332547782769 bayes_pls_golite062009
  • cysteine-type endopeptidase activity
    		•  1.95802900199539 bayes_pls_golite062009
  • tubulin binding
    		•  1.85112496470487 bayes_pls_golite062009
  • microtubule binding
    		•  1.82320858139311 bayes_pls_golite062009
  • binding
    		•  1.77258741259391 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.43988355875744 bayes_pls_golite062009
  • catalytic activity
    		•  1.05972260874031 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.913227912866975 bayes_pls_golite062009
  • protein binding
    		•  0.896934807256194 bayes_pls_golite062009
  • transporter activity
    		•  0.69523261160023 bayes_pls_golite062009
  • DNA binding
    		•  0.683141655614916 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.667279936700542 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.467924587720185 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.439003000540428 bayes_pls_golite062009
  • structural molecule activity
    		•  0.297752217869698 bayes_pls_golite062009
  • calcium-dependent cysteine-type endopeptidase activity
    		•  0.196538841514154 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.125654358663332 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.0241561776323942 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0199148741009585 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle