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The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis. A biological process that results in permanent cessation of all vital functions of a cell. A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells. Cell death resulting from activation of endogenous cellular processes.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: autophagic cell death
Acc: GO:0048102
Aspect: Biological Process
Desc: A form of programmed cell death that is accompanied by macroautophagy, which is characterized by the sequestration of cytoplasmic material within autophagosomes for bulk degradation by lysosomes. Autophagic cell death is characterized by lack of chromatin condensation, massive vacuolization of the cytoplasm, and accumulation of (double-membraned) autophagic vacuoles, with little or no uptake by phagocytic cells.
Synonyms:
  • autophagic death
  • programmed cell death by autophagy
  • type II programmed cell death
Proteins in PDR annotated with:
   This term: 121 [Search]
   Term or descendants: 142 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048102 - autophagic cell death (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle