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Protein Overview: gi|7299843, gi|2...

General Information:
Name(s) found: gi|7299843 [NCBI NR]
gi|21358319 [NCBI NR]
Description(s) found:
Found 8 descriptions.
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  • gi|7299843|gb|AAF55020.1| Kif19A, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|21358319|ref|NP_650337.1| Kif19A, isoform A [Drosophila melanogaster] [NCBI NR]
    • Organism: Drosophila melanogaster
    Length: 728 amino acids

    Gene Ontology:
    Cellular Component: kinesin complex [ISS]
    Biological Process: microtubule-based movement [IEA][ISS]
    Molecular Function: ATP binding [IEA]
    microtubule motor activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MATSAGASSW SGSSGGSNSS QGRSIATAQP AQEERLVVAV RVRPSMEATE RCIEVISGGS  60
   61 LLYDDGGKSR PRQYSYDHVF RENDSQEQVY KTTTAPLTHT MLGPVPRKKP QTSDRAPPTA 120
  121 SCDSTDVSSQ DIGLMVRAIE DIFSHIESAE AYSCRVSISY LEIYNELIRD LLNPGGPLEL 180
  181 REDHRGQRIT VAGLSEITTS SRKEVVSLLL KGNKARTMEP TAANQTSSRS HALLSIMVQA 240
  241 RTPLGTKQGR LFLTDLAGSE RAKKTKNRGK RLQEGAHINR SLLALGNVIN GLSGGARYVN 300
  301 YRDSKLTRLL KEALSGRCKT VMIAHVAPES KHRDETKNTL VYADRANSIT TKLQNSVYID 360
  361 EFKDFPTKHY QSLVSELRDE VSRLRTKMLT ERPRSGAAAA AAAAAASGSA GTAGSGAGSE 420
  421 AVQEQDEQRK TELRYLREQI VLTFKQQMKL RRKLLEAESH LLGLELDAER QHMIISHWQG 480
  481 RIGKLYDAMG DDDIESEGSV ALKNAWGELA AIEKETRRYK EIRERTEHEL EQCRQKGVKL 540
  541 EDELPERISS DEERELLALL CRVHELEADK VSLQAERLAR QAELRRRDLQ LLRAERQRRL 600
  601 CEDIISSQRR LIEEGNVDLP DELRELYGLY QQEIHAGVVT PSTSNYERKL PPIYTAGSDS 660
  661 PGSSSSSEWS PASPLPQIDN QMDPVDRVMG PPVNPRLPRL SAATSANVPA GGSRRPSLRV 720
  721 ARNPHPHP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..369] PSI-BLAST 87.522879 Kinesin
    2 View Details [370..728] PSI-BLAST 6.045757 No description for 2i1jA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • microtubule motor activity
    		•  7.68336791348661 bayes_pls_golite062009
  • plus-end-directed microtubule motor activity
    		•  4.97507344344589 bayes_pls_golite062009
  • microfilament motor activity
    		•  4.176620576177 bayes_pls_golite062009
  • motor activity
    		•  4.04927796049806 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  2.95079405147356 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  2.87427509025394 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  2.85499564954033 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  2.85178667290149 bayes_pls_golite062009
  • actin-dependent ATPase activity
    		•  2.77140616759165 bayes_pls_golite062009
  • tubulin binding
    		•  2.67743463093593 bayes_pls_golite062009
  • microtubule binding
    		•  2.59155206524122 bayes_pls_golite062009
  • transporter activity
    		•  2.58140740499725 bayes_pls_golite062009
  • binding
    		•  2.44689197844883 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  2.4101693596493 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.39695871109024 bayes_pls_golite062009
  • ATPase activity
    		•  2.39535714892224 bayes_pls_golite062009
  • ATPase activity, coupled
    		•  2.18396165590908 bayes_pls_golite062009
  • actin binding
    		•  1.75397031486306 bayes_pls_golite062009
  • hydrolase activity
    		•  1.57549510726226 bayes_pls_golite062009
  • microtubule plus-end binding
    		•  1.36713729043205 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.29730375126024 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  1.07479235523606 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.929901285538132 bayes_pls_golite062009
  • nucleotide binding
    		•  0.922442819194247 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.920987930180051 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.920926158369519 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.906554174337376 bayes_pls_golite062009
  • helicase activity
    		•  0.79055709374547 bayes_pls_golite062009
  • actin filament binding
    		•  0.728264616959762 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.574285918029279 bayes_pls_golite062009
  • GTPase activity
    		•  0.437665353870877 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  0.434775387083003 bayes_pls_golite062009
  • ATP binding
    		•  0.41092997612902 bayes_pls_golite062009
  • guanyl nucleotide binding
    		•  0.399434758448606 bayes_pls_golite062009
  • GTP binding
    		•  0.398333597279278 bayes_pls_golite062009
  • guanyl ribonucleotide binding
    		•  0.39332178627529 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.385813421701492 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.377870145186619 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.355466224802969 bayes_pls_golite062009
  • primary active transmembrane transporter activity
    		•  0.294474570607914 bayes_pls_golite062009
  • P-P-bond-hydrolysis-driven transmembrane transporter activity
    		•  0.282352478532746 bayes_pls_golite062009
  • DNA binding
    		•  0.259361683038035 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
    		•  0.220608508617331 bayes_pls_golite062009
  • ATPase activity, coupled to transmembrane movement of substances
    		•  0.219533217661421 bayes_pls_golite062009
  • ATPase activity, coupled to movement of substances
    		•  0.219157471322311 bayes_pls_golite062009
  • protein transporter activity
    		•  0.178442534411253 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.17029946873911 bayes_pls_golite062009
  • protein binding
    		•  0.071010918255742 bayes_pls_golite062009
  • minus-end-directed microtubule motor activity
    		•  0.068779631341469 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.050107780790998 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0463883764000663 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.0254369227200564 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.0111338193708552 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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