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Protein Overview: pum-PA, pum-PD, ...

General Information:
Name(s) found: FBpp0305823 [FlyBase]
pum-PC / FBpp0081472 [FlyBase]
pum-PD / FBpp0081471 [FlyBase]
pum-PA / FBpp0081470 [FlyBase]
Description(s) found:
Found 53 descriptions.
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  • type=protein; loc=3R:complement(4896667..4897159,4897229..4897397,4897474..4898751,4905467..4905683,4906280..4906744,5039482..5039568,5039699..5039987,5043709..5043827,5043921..5044047,5044244..5044485,5057796..5058578,5059251..5059583); ID=FBpp0305823; name=pum-PG; parent=FBgn0003165,FBtr0333667; dbxref=REFSEQ:NP_001262403,GB_protein:AGB95785,FlyBase:FBpp0305823,FlyBase_Annotation_IDs:CG9755-PG; MD5=bb07091c97f824a925a212e018c37aa6; length=1533; release=r5.56; species=Dmel; [FlyBase]
  • The gene pumilio is referred to in FlyBase by the symbol Dmel\pum (CG9755, FBgn0003165). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4895479..5063417. It has the cytological map location 85C4-85D1. There is experimental evidence that it has the molecular function</span>: SUMO binding. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 130 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; embryonic abdomen; embryonic segment; female germline cyst; anatomical structure; nervous system; peripheral nervous system; germarium; embryonic tagma; embryonic neuron; multi-cell-component structure; cephalopharyngeal skeleton. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene pumilio is referred to in FlyBase by the symbol Dmel\pum (CG9755, FBgn0003165). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4895479..5063417. It has the cytological map location 85C4-85D1. There is experimental evidence that it has the molecular function</span>: SUMO binding. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 130 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; embryonic abdomen; embryonic segment; female germline cyst; anatomical structure; nervous system; peripheral nervous system; germarium; embryonic tagma; embryonic neuron; multi-cell-component structure; cephalopharyngeal skeleton. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene pumilio is referred to in FlyBase by the symbol Dmel\pum (CG9755, FBgn0003165). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4895479..5063417. It has the cytological map location 85C4-85D1. There is experimental evidence that it has the molecular function</span>: SUMO binding. There is experimental evidence that it is involved in the biological process</span>: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 130 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: organ system; embryonic abdomen; embryonic segment; female germline cyst; anatomical structure; nervous system; peripheral nervous system; germarium; embryonic tagma; embryonic neuron; multi-cell-component structure; cephalopharyngeal skeleton. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1533 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [NAS]
    Biological Process: germ cell development [TAS]
    pole cell migration [IMP][TAS]
    positive regulation of translation [TAS]
    anterior/posterior axis specification, embryo [TAS]
    regulation of synaptic growth at neuromuscular junction [IDA]
    head involution [IMP]
    negative regulation of cell cycle [TAS]
    germ-line stem cell division [NAS][TAS]
    synaptic transmission [IMP]
    mitosis [TAS]
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [TAS]
    dendrite morphogenesis [IMP]
    long-term memory [IMP][TAS]
    negative regulation of transcription, DNA-dependent [TAS]
    oogenesis [TAS]
    regulation of synaptic transmission [IMP]
    negative regulation of translation [TAS]
    cell fate determination [TAS]
    cell migration [TAS]
    Molecular Function: SUMO binding [IPI]
    protein binding [TAS]
    translation repressor activity, nucleic acid binding [TAS]
    mRNA binding [ISS][TAS]
    mRNA 3'-UTR binding [TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFLGGNDDR NGRGGVGVGT DAIVGSRGGV SQDAADAAGA AAAAAVGYVF QQRPSPGGVG  60
   61 VGVGGVGGGV PGVGAVGSTL HEAAAAEYAA HFAQKQQQTR WACGDDGHGI DNPDKWKYNP 120
  121 PMNPANAAPG GPPGNGSNGG PGAIGTIGMG SGLGGGGGGG AGGGNNGGSG TNGGLHHQSM 180
  181 AAAAANMAAM QQAAALAKHN HMISQAAAAV AAQQQHQHPH QQHPQQQQQQ QQAQNQGHPH 240
  241 HLMGGGNGLG NGNGLGIQHP GQQQQQQQQQ QQQQHPGQYN ANLLNHAAAL GHMSSYAQSG 300
  301 GSMYDHHGGA MHPGMNGGMP KQQPLGPPGA GGPQDYVYMG GQTTVPMGAA MMPPQNQYMN 360
  361 SSAVAAANRN AAITTSTAKK LWEKSDGKGV SSSTPGGPLH PLQIPGIGDP SSVWKDHTWS 420
  421 TQGENILVPP PSRAYAHGGA SDTSNSGNAG ILSPRDSTCA KVVEYVFSGS PTNKDSSLSG 480
  481 LEPHLRNLKF DDNDKSRDDK EKANSPFDTN GLKKDDQVTN SNGVVNGIDD DKGFNRTPGS 540
  541 RQPSPAEESQ PRPPNLLFPP LPFNHMLMDH GQGMGGGLGG VVGSGNGVGG GSGGGGAGGA 600
  601 YAAHQQMAAQ MSQLQPPMMN GVGGGMPMAA QSPMLNHQAA GPNHMESPGN LLQQQNFDVQ 660
  661 QLFRSQNPGL AAVATNAAAA AAAAAAATSA ASAAAAVGAP PVPNGSLQQS QQQQQQQQQQ 720
  721 QQQQQMHMAA ASQQFLAAQQ QAQNAAYAAQ QATSYVINPG QEAAPYMGMI AAAQMPYYGV 780
  781 APWGMYPGNL IPQQGTQPRR PLTPSQQGAE NQPYQVIPAF LDHTGSLLMG GPRTGTPMRL 840
  841 VSPAPVLVPP GATRAGPPPP QGPQLYQPQP QTAQQNLYSQ QNGSSVGGLA LNTSSLTGRR 900
  901 DSFDRSTSAF SPSTMDYTSS GVAAAANAVN STVAQAAAAA AAAAAARGKW PGAMSGAASG 960
  961 AYGALGAGNA SASPLGAPIT PPPSAQSCLL GSRAPGAESR QRQQQQQQLA AVGLPATAAA1020
 1021 AQAAVAAAAN NMFGSNSSIF SNPLAIPGTA AVAAAAAAAA AANSRQVAAT AAAAAAVAAA1080
 1081 AGGVGGAPQP GRSRLLEDFR NQRYPNLQLR DLANHIVEFS QDQHGSRFIQ QKLERATAAE1140
 1141 KQMVFSEILA AAYSLMTDVF GNYVIQKFFE FGTPEQKNTL GMQVKGHVLQ LALQMYGCRV1200
 1201 IQKALESISP EQQQEIVHEL DGHVLKCVKD QNGNHVVQKC IECVDPVALQ FIINAFKGQV1260
 1261 YSLSTHPYGC RVIQRILEHC TAEQTTPILD ELHEHTEQLI QDQYGNYVIQ HVLEHGKQED1320
 1321 KSILINSVRG KVLVLSQHKF ASNVVEKCVT HATRGERTGL IDEVCTFNDN ALHVMMKDQY1380
 1381 ANYVVQKMID VSEPTQLKKL MTKIRPHMAA LRKYTYGKHI NAKLEKYYMK ITNPITVGTG1440
 1441 AGGVPAASSA AAVSSGATSA SVTACTSGSS TTTTSTTNSL ASPTICSVQE NGSAMVVEPS1500
 1501 SPDASESSSS VVSGAVNSSL GPIGPPTNGN VVL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..118] deduced N/A No confident structure predictions are available.
    2 View Details [119..1096] PSI-BLAST 26.39794 No description for 1y0fB was found.
    3 View Details [1097..1436] PSI-BLAST 170.0 Pumilio 1
    4 View Details [1437..1533] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  0.373576425899935 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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