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Protein Overview: VEGFA_RAT

General Information:
Name(s) found: VEGFA_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Vascular endothelial growth factor A OS=Rattus norvegicus GN=Vegfa PE=1 SV=2 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 214 amino acids

    Gene Ontology:
    Cellular Component: platelet alpha granule lumen [UNKNOWN]
    basement membrane [IDA]
    extracellular space [UNKNOWN][IDA]
    membrane-bounded vesicle [IDA]
    cytoplasm [UNKNOWN][IEA]
    secretory granule [UNKNOWN]
    membrane [IEA]
    extracellular region [UNKNOWN][IEA]
    cell surface [UNKNOWN][IEA]
    Biological Process: mesoderm development [UNKNOWN][IEA]
    blood vessel morphogenesis [UNKNOWN]
    negative regulation of programmed cell death [IMP]
    branching morphogenesis of a tube [UNKNOWN]
    behavior [UNKNOWN][IEA]
    positive regulation of angiogenesis [UNKNOWN]
    lung alveolus development [IMP]
    heart morphogenesis [UNKNOWN][IEA]
    response to hypoxia [UNKNOWN][IDA]
    anti-apoptosis [UNKNOWN][IEA]
    in utero embryonic development [UNKNOWN][IEA]
    kidney development [UNKNOWN][IEA]
    vasculature development [UNKNOWN]
    positive regulation of vascular endothelial growth factor receptor signaling pathway [UNKNOWN][IEA]
    post-embryonic camera-type eye development [UNKNOWN][IEA]
    cellular response to hypoxia [UNKNOWN]
    positive regulation of epithelial cell proliferation [UNKNOWN][IEA]
    positive regulation of positive chemotaxis [UNKNOWN]
    eye photoreceptor cell development [UNKNOWN][IEA]
    platelet-derived growth factor receptor signaling pathway [UNKNOWN][IEA]
    artery morphogenesis [UNKNOWN][IEA]
    positive regulation of mesenchymal cell proliferation [UNKNOWN][IEA]
    primitive erythrocyte differentiation [UNKNOWN][IEA]
    positive regulation of signal transduction [IDA]
    negative regulation of bone resorption [IMP]
    growth [UNKNOWN][IEA]
    positive regulation of mast cell chemotaxis [UNKNOWN]
    basophil chemotaxis [UNKNOWN]
    positive regulation of vascular permeability [UNKNOWN][IMP]
    epithelial cell differentiation [UNKNOWN][IEA]
    vascular endothelial growth factor receptor signaling pathway [UNKNOWN][IMP]
    mRNA stabilization [IDA]
    positive regulation of cell migration [UNKNOWN]
    cell proliferation [UNKNOWN]
    regulation of cell shape [UNKNOWN][IEA]
    multicellular organismal development [IEA]
    positive regulation of cell proliferation [UNKNOWN][IMP][TAS]
    nervous system development [IDA][NAS]
    positive regulation of cellular component movement [UNKNOWN]
    lactation [UNKNOWN][IEA]
    positive regulation of transcription from RNA polymerase II promoter [IDA]
    cardiac muscle fiber development [UNKNOWN][IEA]
    surfactant homeostasis [UNKNOWN][IEA]
    positive regulation of smooth muscle cell proliferation [IMP]
    response to cold [IEP]
    blood vessel development [UNKNOWN]
    positive regulation of cell division [IEA]
    mammary gland alveolus development [UNKNOWN][IEA]
    angiogenesis [UNKNOWN][IMP][TAS]
    patterning of blood vessels [UNKNOWN][IEA]
    positive regulation of endothelial cell migration [UNKNOWN]
    cell migration [UNKNOWN][IEA]
    positive regulation of peptidyl-tyrosine phosphorylation [UNKNOWN]
    lung development [UNKNOWN]
    induction of positive chemotaxis [UNKNOWN]
    T-helper 1 type immune response [IDA]
    cell maturation [UNKNOWN][IEA]
    positive regulation of blood vessel endothelial cell migration [UNKNOWN][IEA]
    ovarian follicle development [UNKNOWN][IEA]
    camera-type eye morphogenesis [UNKNOWN][IEA]
    blood vessel remodeling [IMP]
    negative regulation of apoptosis [UNKNOWN]
    positive regulation of endothelial cell proliferation [UNKNOWN][IEA]
    Molecular Function: growth factor activity [UNKNOWN][IDA]
    vascular endothelial growth factor receptor 1 binding [UNKNOWN][IEA]
    protein binding [UNKNOWN]
    protein homodimerization activity [IDA]
    platelet-derived growth factor receptor binding [UNKNOWN][IEA]
    vascular endothelial growth factor receptor binding [UNKNOWN][TAS]
    vascular endothelial growth factor receptor 2 binding [UNKNOWN][IEA][IMP]
    protein heterodimerization activity [UNKNOWN]
    fibronectin binding [UNKNOWN][IEA]
    chemoattractant activity [UNKNOWN]
    heparin binding [UNKNOWN][IEA]
    cell surface binding [UNKNOWN][IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNFLLSWVHW TLALLLYLHH AKWSQAAPTT EGEQKAHEVV KFMDVYQRSY CRPIETLVDI  60
   61 FQEYPDEIEY IFKPSCVPLM RCAGCCNDEA LECVPTSESN VTMQIMRIKP HQSQHIGEMS 120
  121 FLQHSRCECR PKKDRTKPEK KSVRGKGKGQ KRKRKKSRFK SWSVHCEPCS ERRKHLFVQD 180
  181 PQTCKCSCKN TDSRCKARQL ELNERTCRCD KPRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle