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Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. Any process that stops, prevents or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway. The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: platelet-derived growth factor receptor signaling pathway
Acc: GO:0048008
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
Synonyms:
  • PDGF receptor signaling pathway
  • PDGFR signaling pathway
  • PDGF receptor signalling pathway
Proteins in PDR annotated with:
   This term: 53 [Search]
   Term or descendants: 60 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048008 - platelet-derived growth factor receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle