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Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands. Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity. The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate. The series of molecular signals generated as a consequence of a transmembrane receptor tyrosine kinase binding to its physiological ligand. Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: vascular endothelial growth factor receptor signaling pathway
Acc: GO:0048010
Aspect: Biological Process
Desc: The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands.
Synonyms:
  • VEGF receptor signalling pathway
  • VEGF receptor signaling pathway
  • VEGFR signaling pathway
Proteins in PDR annotated with:
   This term: 56 [Search]
   Term or descendants: 71 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0048010 - vascular endothelial growth factor receptor signaling pathway (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle