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Protein Overview: AKT1_RAT

General Information:
Name(s) found: AKT1_RAT [Swiss-Prot]
Description(s) found:
Found 21 descriptions.
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  • RAC-alpha serine/threonine-protein kinase OS=Rattus norvegicus GN=Akt1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 480 amino acids

    Gene Ontology:
    Cellular Component: nucleus [UNKNOWN][IEA]
    microtubule cytoskeleton [UNKNOWN]
    soluble fraction [IDA]
    cytoskeleton [IEA]
    cytoplasm [UNKNOWN][IDA]
    spindle [UNKNOWN][IEA]
    cytosol [UNKNOWN][IDA]
    plasma membrane [UNKNOWN][IEA]
    nucleoplasm [UNKNOWN]
    lamellipodium [UNKNOWN][IEA]
    Biological Process: response to food [UNKNOWN][IEA]
    cell projection organization [IDA]
    positive regulation of fat cell differentiation [UNKNOWN][IEA]
    regulation of survival gene product expression [UNKNOWN][IEA]
    positive regulation of glycogen biosynthetic process [UNKNOWN]
    inflammatory response [UNKNOWN][IEA]
    positive regulation of cell growth [UNKNOWN][IDA]
    negative regulation of fatty acid beta-oxidation [UNKNOWN][IEA]
    anti-apoptosis [IMP][TAS]
    positive regulation of nitric-oxide synthase activity [UNKNOWN][IEA]
    protein import into nucleus, translocation [UNKNOWN][IEA]
    apoptosis [UNKNOWN]
    regulation of neuron projection development [ISS]
    regulation of protein localization [UNKNOWN]
    insulin-like growth factor receptor signaling pathway [UNKNOWN][ISS]
    response to hormone stimulus [IEA]
    translation [IMP]
    activation of pro-apoptotic gene products [UNKNOWN]
    activation-induced cell death of T cells [UNKNOWN][IEA]
    positive regulation of glucose metabolic process [UNKNOWN][IEA]
    labyrinthine layer blood vessel development [UNKNOWN][IEA]
    negative regulation of plasma membrane long-chain fatty acid transport [UNKNOWN][IEA]
    glucose transport [IEA]
    peptidyl-serine phosphorylation [UNKNOWN][IDA]
    regulation of cell migration [IMP]
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process [UNKNOWN][IEA]
    protein ubiquitination [UNKNOWN][IEA]
    positive regulation of cellular protein metabolic process [IMP]
    positive regulation of nitric oxide biosynthetic process [UNKNOWN][IEA]
    insulin receptor signaling pathway [UNKNOWN][IMP][ISS]
    nervous system development [IEA]
    carbohydrate transport [IEA]
    protein amino acid phosphorylation [UNKNOWN][IDA][ISS]
    negative regulation of protein kinase activity [UNKNOWN][IDA]
    maternal placenta development [UNKNOWN][IEA]
    regulation of translation [IEA]
    positive regulation of cyclin-dependent protein kinase activity involved in G1/S [UNKNOWN][IEA]
    cellular response to insulin stimulus [UNKNOWN][IMP]
    glycogen cell development involved in embryonic placenta development [UNKNOWN][IEA]
    response to UV-A [UNKNOWN][IEA]
    protein kinase B signaling cascade [UNKNOWN][IEA]
    apoptotic mitochondrial changes [UNKNOWN][IEA]
    negative regulation of cell size [IDA]
    response to fluid shear stress [UNKNOWN][IEA]
    germ cell development [UNKNOWN][IEA]
    signal transduction [IDA]
    positive regulation of establishment of protein localization in plasma membrane [UNKNOWN][IEA]
    protein catabolic process [UNKNOWN][IEA]
    positive regulation of glucose import [UNKNOWN][IEA]
    anagen [UNKNOWN][IEA]
    negative regulation of JNK cascade [IDA]
    positive regulation of lipid biosynthetic process [UNKNOWN][IEA]
    carbohydrate metabolic process [IEA]
    glycogen biosynthetic process [IMP]
    glycogen metabolic process [UNKNOWN]
    intracellular signaling pathway [UNKNOWN][IEA]
    regulation of glycogen biosynthetic process [UNKNOWN]
    negative regulation of apoptosis [UNKNOWN]
    positive regulation of sodium ion transport [UNKNOWN][IEA]
    Molecular Function: nucleotide binding [IEA]
    phosphatidylinositol-3,4,5-trisphosphate binding [UNKNOWN][IEA]
    ATP binding [IDA]
    identical protein binding [UNKNOWN][IEA]
    protein binding [UNKNOWN][IDA][IPI]
    protein kinase activity [UNKNOWN][IDA]
    protein serine/threonine kinase activity [UNKNOWN][IDA][ISS][TAS]
    transferase activity [IEA]
    nitric-oxide synthase regulator activity [UNKNOWN][IEA]
    phosphatidylinositol-3,4-bisphosphate binding [UNKNOWN][IEA]
    kinase activity [UNKNOWN]
    enzyme binding [IPI]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNDVAIVKEG WLHKRGEYIK TWRPRYFLLK NDGTFIGYKE RPQDVEQRES PLNNFSVAQC  60
   61 QLMKTERPRP NTFIIRCLQW TTVIERTFHV ETPEEREEWT TAIQTVADGL KRQEEETMDF 120
  121 RSGSPSDNSG AEEMEVALAK PKHRVTMNEF EYLKLLGKGT FGKVILVKEK ATGRYYAMKI 180
  181 LKKEVIVAKD EVAHTLTENR VLQNSRHPFL TALKYSFQTH DRLCFVMEYA NGGELFFHLS 240
  241 RERVFSEDRA RFYGAEIVSA LDYLHSEKNV VYRDLKLENL MLDKDGHIKI TDFGLCKEGI 300
  301 KDGATMKTFC GTPEYLAPEV LEDNDYGRAV DWWGLGVVMY EMMCGRLPFY NQDHEKLFEL 360
  361 ILMEEIRFPR TLGPEAKSLL SGLLKKDPTQ RLGGGSEDAK EIMQHRFFAN IVWQDVYEKK 420
  421 LSPPFKPQVT SETDTRYFDE EFTAQMITIT PPDQDDSMEC VDSERRPHFP QFSYSASGTA 480
  481

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle