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Any process that stops, prevents or reduces the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. The process whereby a signal is conveyed via the transfer of one or more phosphate groups. The process whereby a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. Any process that activates or increases the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B, which occurs as a result of a single trigger reaction or compound. Any process that modulates the frequency, rate or extent of the protein kinase B signaling cascade, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B. A series of reactions that occur within the cell, mediated by protein kinases, which occurs as a result of a single trigger reaction or compound.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: protein kinase B signaling cascade
Acc: GO:0043491
Aspect: Biological Process
Desc: A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B, which occurs as a result of a single trigger reaction or compound.
Synonyms:
  • PKB signalling cascade
  • protein kinase B signalling cascade
  • AKT signaling cascade
  • AKT signalling cascade
  • PKB signaling cascade
Proteins in PDR annotated with:
   This term: 19 [Search]
   Term or descendants: 89 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0043491 - protein kinase B signaling cascade (interactive image map)
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