General Information: |
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Name(s) found: |
PPARG_RAT
[Swiss-Prot]
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Description(s) found:
SHOW ONLY BEST |
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Organism: | Rattus norvegicus |
Length: | 505 amino acids |
Gene Ontology: |
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Cellular Component: |
nucleus
[UNKNOWN][IDA]
cytosol [UNKNOWN][IDA] |
Biological Process: |
response to estrogen stimulus
[IEP]
response to low-density lipoprotein stimulus [UNKNOWN][IEA] positive regulation of fat cell differentiation [UNKNOWN][ISS] fat cell differentiation [UNKNOWN] regulation of transcription [UNKNOWN] positive regulation of transcription factor activity [UNKNOWN] positive regulation of oligodendrocyte differentiation [IMP] white fat cell differentiation [UNKNOWN][ISS] brown fat cell differentiation [UNKNOWN][IEA] long-chain fatty acid transport [UNKNOWN][IEA] negative regulation of transcription, DNA-dependent [UNKNOWN] induction of apoptosis [UNKNOWN] negative regulation of cell growth [IMP] activation of caspase activity [UNKNOWN] monocyte differentiation [UNKNOWN][IEA] response to organic substance [IEP] response to organic cyclic substance [IEP] epithelial cell differentiation [UNKNOWN][IEA] fatty acid oxidation [IMP] glucose homeostasis [UNKNOWN][IEA] negative regulation of macrophage derived foam cell differentiation [UNKNOWN][IEA] organ regeneration [IEP] negative regulation of telomerase activity [IMP] negative regulation of cell proliferation [UNKNOWN][IMP] positive regulation of transcription [UNKNOWN][IEA] placenta development [UNKNOWN][IEA] positive regulation of transcription from RNA polymerase II promoter [UNKNOWN] lipoprotein transport [UNKNOWN][IEA] negative regulation of transcription from RNA polymerase II promoter [UNKNOWN] cellular response to insulin stimulus [UNKNOWN][IEA] heart development [IEP] response to cold [IEP] positive regulation of fatty acid oxidation [IMP] response to lipid [IEA] positive regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IDA] negative regulation of receptor biosynthetic process [UNKNOWN][IEA] negative regulation of gene-specific transcription from RNA polymerase II promoter [UNKNOWN][IEA] negative regulation of sequestering of triglyceride [UNKNOWN][IEA] signal transduction [UNKNOWN][IEA] cell maturation [UNKNOWN][IEA] regulation of fat cell differentiation [UNKNOWN][IDA] low-density lipoprotein receptor biosynthetic process [UNKNOWN][IEA] regulation of blood pressure [UNKNOWN][IEA] fatty acid metabolic process [TAS] negative regulation of acute inflammatory response [IMP] regulation of transcription from RNA polymerase II promoter [IEP] response to drug [IEP] cell fate commitment [UNKNOWN][IEA] response to caffeine [IEP] negative regulation of cholesterol storage [UNKNOWN][IEA] response to vitamin A [IEP] negative regulation of cytokine production [IEA] regulation of lipid metabolic process [IMP] |
Molecular Function: |
zinc ion binding
[IEA]
drug binding [UNKNOWN][IEA] sequence-specific DNA binding [UNKNOWN] chromatin binding [UNKNOWN][IEA] retinoid X receptor binding [UNKNOWN][IEA] DNA binding [UNKNOWN][IDA] transcription factor activity [UNKNOWN][IDA] protein binding [UNKNOWN] ligand-dependent nuclear receptor activity [UNKNOWN] metal ion binding [IEA] steroid hormone receptor activity [IEA] promoter binding [UNKNOWN][IDA] transcription activator activity [UNKNOWN][IEA] transcription repressor activity [UNKNOWN] transcription activator binding [UNKNOWN][IEA] specific transcriptional repressor activity [IEA] arachidonic acid binding [IEA] |
Sequence: |
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Sequence: [PDR BLAST] [ProtParam] |
1 11 21 31 41 51 | | | | | | 1 MGETLGDPPV DPEHGAFADA LPMSTSQEIT MVDTEMPFWP TNFGISSVDL SVMDDHSHSF 60 61 DIKPFTTVDF SSISAPHYED IPFTRADPMV ADYKYDLKLQ EYQSAIKVEP ASPPYYSEKT 120 121 QLYNRPHEEP SNSLMAIECR VCGDKASGFH YGVHACEGCK GFFRRTIRLK LIYDRCDLNC 180 181 RIHKKSRNKC QYCRFQKCLA VGMSHNAIRF GRMPQAEKEK LLAEISSDID QLNPESADLR 240 241 ALAKHLYDSY IKSFPLTKAK ARAILTGKTT DKSPFVIYDM NSLMMGEDKI KFKHITPLQE 300 301 QSKEVAIRIF QGCQFRSVEA VQEITEYAKN IPGFINLDLN DQVTLLKYGV HEIIYTMLAS 360 361 LMNKDGVLIS EGQGFMTREF LKSLRKPFGD FMEPKFEFAV KFNALELDDS DLAIFIAVII 420 421 LSGDRPGLLN VKPIEDIQDN LLQALELQLK LNHPESSQLF AKVLQKMTDL RQIVTEHVQL 480 481 LHVIKKTETD MSLHPLLQEI YKDLY |
NOT SHOWING SINGLE HITS. [ Show Single Hits ]
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Protein predicted to be: | GLOBULAR (No transmembrane regions or signal peptide) |
Confidence of classification: | 0.99 |
Source: Reynolds et al. (2008)