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Protein Overview: CALCA_RAT

General Information:
Name(s) found: CALCA_RAT [Swiss-Prot]
Description(s) found:
Found 12 descriptions.
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  • Calcitonin gene-related peptide 1 OS=Rattus norvegicus GN=Calca PE=2 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 128 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    extracellular space [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IEA]
    terminal button [UNKNOWN][IEA]
    neuronal cell body [UNKNOWN][IEA]
    extracellular region [UNKNOWN][IEA]
    neuron projection [UNKNOWN]
    intracellular [UNKNOWN][IEA]
    axon [UNKNOWN][IDA]
    Biological Process: positive regulation of vasodilation [UNKNOWN]
    feeding behavior [UNKNOWN][IEA]
    positive regulation of adenylate cyclase activity [UNKNOWN]
    vasodilation [IDA]
    endothelial cell migration [UNKNOWN]
    positive regulation of cell adhesion [UNKNOWN]
    leukocyte cell-cell adhesion [UNKNOWN]
    negative regulation of smooth muscle contraction [UNKNOWN][IMP]
    [NOT]neuromuscular junction development [UNKNOWN]
    response to pain [UNKNOWN][IEA]
    vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure [UNKNOWN][IEA]
    inflammatory response [UNKNOWN]
    response to heat [UNKNOWN][IEA]
    positive regulation of macrophage differentiation [UNKNOWN]
    vasculature development [UNKNOWN]
    elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger [UNKNOWN]
    negative regulation of osteoclast differentiation [UNKNOWN]
    activation of protein kinase activity [UNKNOWN]
    activation of adenylate cyclase activity [UNKNOWN]
    regulation of heart contraction [IDA]
    cytosolic calcium ion homeostasis [UNKNOWN]
    negative regulation of blood pressure [UNKNOWN][IMP]
    activation of adenylate cyclase activity by G-protein signaling pathway [UNKNOWN][IEA]
    aging [IEP]
    negative regulation of bone resorption [UNKNOWN]
    [NOT]regulation of blood pressure [UNKNOWN]
    embryo implantation [UNKNOWN]
    cellular calcium ion homeostasis [UNKNOWN][IEA]
    elevation of cytosolic calcium ion concentration [UNKNOWN]
    positive regulation of ossification [UNKNOWN][IEA]
    regulation of heart rate [UNKNOWN][IEA]
    neuropeptide signaling pathway [UNKNOWN][IEA]
    positive regulation of interleukin-8 production [UNKNOWN]
    neurological system process involved in regulation of systemic arterial blood pressure [UNKNOWN]
    negative regulation of transcription [UNKNOWN]
    endothelial cell proliferation [UNKNOWN]
    negative regulation of calcium ion transport into cytosol [UNKNOWN]
    positive regulation of interleukin-1 alpha production [UNKNOWN]
    regulation of inflammatory response [IMP]
    negative regulation of ossification [UNKNOWN][IEA]
    negative regulation of neurological system process [UNKNOWN][IEA]
    detection of temperature stimulus involved in sensory perception of pain [UNKNOWN][IEA]
    Molecular Function: protein binding [UNKNOWN]
    calcitonin receptor binding [UNKNOWN][IMP][TAS]
    neuropeptide hormone activity [TAS]
    receptor binding [UNKNOWN]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGFLKFSPFL VVSILLLYQA CGLQAVPLRS TLESSPGMAA TLSEEEARLL LAALVQNYMQ  60
   61 MKVRELEQEQ EAEGSSVTAQ KRSCNTATCV THRLAGLLSR SGGVVKDNFV PTNVGSEAFG 120
  121 RRRRDLQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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