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Protein Overview: MK09_RAT

General Information:
Name(s) found: MK09_RAT [Swiss-Prot]
Description(s) found:
Found 20 descriptions.
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  • Mitogen-activated protein kinase 9 OS=Rattus norvegicus GN=Mapk9 PE=1 SV=1 [Swiss-Prot]
    • Organism: Rattus norvegicus
    Length: 423 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    cytoplasm [IDA]
    mitochondrion [IDA]
    cytosolic part [IDA]
    nucleoplasm [UNKNOWN]
    Biological Process: response to cytokine stimulus [IEP]
    positive regulation of nitric oxide biosynthetic process [IMP]
    positive regulation of transcription [IMP]
    JNK cascade [UNKNOWN][IDA]
    protein amino acid phosphorylation [IDA][IEA]
    response to toxin [IEP]
    JUN phosphorylation [IMP]
    response to mechanical stimulus [IEP]
    positive regulation of prostaglandin secretion [IMP]
    induction of apoptosis in response to chemical stimulus [UNKNOWN]
    cellular response to UV [IMP]
    regulation of protein ubiquitination [IMP]
    positive regulation of chemokine production [IMP]
    response to protein stimulus [IEP][IMP]
    response to organic substance [IEP]
    positive regulation of cell morphogenesis involved in differentiation [IMP]
    positive regulation of prostaglandin biosynthetic process [IMP]
    neuron projection development [IMP]
    response to amine stimulus [IEP]
    response to cadmium ion [UNKNOWN]
    regulation of JNK cascade [IMP]
    protein targeting to mitochondrion [IEP]
    positive regulation of caspase activity [IMP]
    central nervous system development [IEP]
    positive regulation of nitric-oxide synthase 2 biosynthetic process [IMP]
    positive regulation of gene expression [UNKNOWN]
    response to drug [IMP]
    positive regulation of protein amino acid phosphorylation [IMP]
    positive regulation of apoptosis [IMP]
    release of cytochrome c from mitochondria [IMP]
    response to lipopolysaccharide [IEP]
    positive regulation of macrophage derived foam cell differentiation [UNKNOWN]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IDA][IEA]
    protein binding [UNKNOWN][IDA][IPI]
    JUN kinase activity [UNKNOWN][IDA][IMP]
    MAP kinase activity [IEA]
    protein serine/threonine kinase activity [UNKNOWN][IEA]
    transferase activity [IEA]
    mitogen-activated protein kinase kinase kinase binding [IPI]
    caspase activator activity [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDSKSDGQF YSVQVADSTF TVLKRYQQLK PIGSGAQGIV CAAFDTVLGI NVAVKKLSRP  60
   61 FQNQTHAKRA YRELVLLKCV NHKNIISLLN VFTPQKTLEE FQDVYLVMEL MDANLCQVIH 120
  121 MELDHERMSY LLYQMLCGIK HLHSAGIIHR DLKPSNIVVK SDCTLKILDF GLARTACTNF 180
  181 MMTPYVVTRY YRAPEVILGM GYKENVDIWS VGCIMGELVK GCVIFQGTDH IDQWNKVIEQ 240
  241 LGTPSAEFMK KLQPTVRNYV ENRPKYPGIK FEELFPDWIF PSESERDKIK TSQARDLLSK 300
  301 MLVIDPDKRI SVDEALRHPY ITVWYDPAEA EAPPPQIYDA QLEEREHAIE EWKELIYKEV 360
  361 MDWEERSKNG VKDQPSDAAV SSKATPSQSS SINDISSMST EHTLASDTDS SLDASTGPLE 420
  421 GCR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle