Protein Overview: gi|149057556, gi...

General Information:
Name(s) found:	gi\|27703746 [NCBI NR] gi\|157824095 [NCBI NR] gi\|149057557 [NCBI NR] gi\|149057556 [NCBI NR] gi\|109504409 [NCBI NR]
Description(s) found: SHOW ONLY BEST	gi\|27703746\|ref\|XP_225045.1\| PREDICTED: similar to DNA ligase IV [Rattus norvegicus] [NCBI NR] gi\|157824095\|ref\|NP_001099565.1\| ligase IV, DNA, ATP-dependent [Rattus norvegicus] [NCBI NR] gi\|149057557\|gb\|EDM08800.1\| rCG42995, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|149057556\|gb\|EDM08799.1\| rCG42995, isoform CRA_a [Rattus norvegicus] [NCBI NR] gi\|109504409\|ref\|XP_001067682.1\| PREDICTED: similar to DNA ligase IV [Rattus norvegicus] [NCBI NR] Ensembl_locations(Chr-bp):16-80521713 [hmr_yeast5_DM3-1_pombe.fasta] similar to ligase IV, DNA, ATP-dependent; ligase IV; DNA ligase IV [HMR_022704-rand.fasta] similar to ligase IV, DNA, ATP-dependent; ligase IV; DNA ligase IV [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 PREDICTED: similar to ligase IV, DNA, ATP-dependent [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] Tax_Id=10116 Similar to ligaSe IV, DNA, ATP-dependent [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta] ligase IV, DNA, ATP-dependent [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] rCG42995, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 SIMILAR TO LIGASE IV, DNA, ATP-DEPENDENT [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] PREDICTED: similar to DNA ligase IV [Rattus norvegicus] [nr-271106-contam.fasta] Tax_Id=10116 Gene_Symbol=Lig4 ligase IV, DNA, ATP-dependent [rat-ipi-250309-contam.fasta] DNA ligase OS=Rattus norvegicus GN=Lig4 [011711_HMR.fasta] DNA ligase OS=Rattus norvegicus GN=Lig4 PE=3 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
Organism:	Rattus norvegicus
Length:	911 amino acids
Gene Ontology:
Cellular Component:	condensed chromosome [UNKNOWN] nucleus [UNKNOWN][IDA] nonhomologous end joining complex [UNKNOWN] DNA-dependent protein kinase-DNA ligase 4 complex [UNKNOWN] DNA ligase IV complex [UNKNOWN] cellular_component [ND] intracellular [IEA]
Biological Process:	cell proliferation [UNKNOWN] DNA repair [UNKNOWN][IEA] response to X-ray [UNKNOWN] DNA replication [IEA] DNA ligation [UNKNOWN][IDA] double-strand break repair via nonhomologous end joining [UNKNOWN] double-strand break repair [UNKNOWN] negative regulation of neuron apoptosis [UNKNOWN] DNA ligation involved in DNA repair [UNKNOWN] DNA ligation involved in DNA recombination [UNKNOWN] in utero embryonic development [UNKNOWN] positive regulation of fibroblast proliferation [UNKNOWN] provirus integration [UNKNOWN] somatic stem cell maintenance [UNKNOWN] response to gamma radiation [UNKNOWN] neuron apoptosis [UNKNOWN] response to ionizing radiation [UNKNOWN] isotype switching [UNKNOWN] V(D)J recombination [UNKNOWN] biological_process [ND] T cell differentiation in the thymus [UNKNOWN] T cell receptor V(D)J recombination [UNKNOWN] immunoglobulin V(D)J recombination [UNKNOWN] DNA recombination [IEA] nucleotide-excision repair, DNA gap filling [UNKNOWN] single strand break repair [UNKNOWN] cellular response to lithium ion [IEP] central nervous system development [UNKNOWN] pro-B cell differentiation [UNKNOWN] chromosome organization [UNKNOWN] initiation of viral infection [UNKNOWN] positive regulation of neurogenesis [UNKNOWN]
Molecular Function:	DNA binding [UNKNOWN][IDA][IEA] ATP binding [UNKNOWN][IDA][IEA] DNA ligase (ATP) activity [UNKNOWN][IDA][IEA] protein binding [UNKNOWN] protein C-terminus binding [UNKNOWN] DNA ligase activity [UNKNOWN] molecular_function [ND] ligase activity [UNKNOWN]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSQASRTV AAHVPFADLC STLERIQKGK DRAEKIRHFK EFLDSWRKFH DALHKNKKDV  60
   61 PDSFYPAMRL ILPQLERERM AYGIKETMLA KLYIELLNLP REGKDAQKLL NYRTPSGARS 120
  121 DAGDFATIAY FVLKPRCLQK GSLTIQKVNE LLDLVASNNS GKRKDLVKKS LLQLITQCSA 180
  181 LEQKWLIRMI IKDLKLGVSQ HTILSIFHND AVELHNVTTD LEKVCRQLHD PSVGLSDISI 240
  241 TLFSAFRPML AAVADVERVE KDMKQQSFYI ETKLDGERMQ MHKDGALYRY FSRNGYNYTD 300
  301 QFGESPQEGS LTPFIHNAFK TDVQVCILDG EMMAYNPTTQ TFMQKGVKFD IKRMVEDSDL 360
  361 QTCYCVFDVL MVNNKKLGRE TLRKRYDILS STFTPIQGRI EIVQKTQAQT KQEVVDALND 420
  421 AIDKREEGIM VKHPLSIYKP DKRGEGWLKI KPEYVTGLMD ELDLLIVGGY WGKGSRGGMM 480
  481 SHFLCAVAET PPPGDKPSVF HTLCRVGSGY TMKELYDLGL KLAKYWKPFQ RKSPPSCILC 540
  541 GTEKPEVYIE PQNSVIVQIK AAEIVPSDMY KTGSTLRFPR IEKIRDDKEW HDCMTLDDLE 600
  601 QLRGKASGKL ATKHLHIGDD DEPREKRRKP ISKTKKTIGI IEHLKAPNLS NINKVSNVFE 660
  661 DVEFCVMSGL DGYPKPDLEN KIAEFGGYIV QNPGPDTYCV IAGSENIRVR NIISSDRHDV 720
  721 VKPEWLLECF KTKTCVPWQP RFMIHMCPST KQHFAREYDC YGDSYFVDAD LDQLKEVFLR 780
  781 IKPSEQQTPE EMAPVIADLE CRYSWDHSPL SMFRHYTVYL DLYAVINDLS SKIEATRLGV 840
  841 TALELRFRGA KVVSRLSEGV SHVIIGEDQR RVSDFKTFRR TLKKKFKILQ ERWVIDSVDK 900
  901 CELQEENLYL L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.94

Protein Overview: gi|149057556, gi...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: