Protein Overview: DNLI4_MOUSE, DNL...

General Information:
Name(s) found:	DNLI4_MOUSE [Swiss-Prot] DNL4_MOUSE [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|81875132\|sp\|Q8BTF7.1\|DNLI4_MOUSE RecName: Full=DNA ligase 4; AltName: Full=DNA ligase IV; AltName: Full=Polydeoxyribonucleotide synthase [ATP] 4 [NCBI NR] ref\|NP_795927.1\| ligase IV, DNA, ATP-dependent [Mus musculus] [NCBI NR] gi\|26326007\|dbj\|BAC26747.1\| unnamed protein product [Mus musculus] [NCBI NR] DNA ligase 4 OS=Mus musculus GN=Lig4 PE=2 SV=1 [Swiss-Prot] DNA ligase 4 - Mus musculus (Mouse) [Swiss-Prot] Ensembl_locations(Chr-bp):8-9979895 DNA ligase IV [hmr_yeast5_DM3-1_pombe.fasta] ligase IV, DNA, ATP-dependent; DNA ligase IV [HMR_022704-rand.fasta] Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932416F16 product:DNA LIGASE IV (EC 6.5.1.1) (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [ipi.MOUSE.v3.06.fasta] ligase IV, DNA, ATP-dependent [Mus musculus]gi\|26326007\|dbj\|BAC26747.1\| unnamed protein product [Mus musculus] [nrdb_11152004_Chlamydomonas] Tax_Id=10090 DNA ligase 4 [EBI-IPI_mouse_3.17_05-10-2006_con_reversed.fasta] ligase IV, DNA, ATP-dependent [Mus musculus] [mouse-NCBI-010306_contam_rand.fasta] Tax_Id=10090 Mus musculus adult male testis cDNA, RIKEN full-length enriched library, clone:4932416F16 product:DNA LIGASE IV (EC 6.5.1.1) (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [EBI-IPI_mouse_3.06_05-10-2005_origrev_con.fasta] DNA ligase 4 (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] unnamed protein product [Mus musculus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10090 MUS MUSCULUS ADULT MALE TESTIS CDNA, RIKEN FULL-LENGTH ENRICHED LIBRARY, CLONE:4932416F16 PRODUCT:DNA LIGASE IV (EC 6.5.1.1) (POLYDEOXYRIBONUCLEOTIDE SYNTHASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10090 Gene_Symbol=Lig4 DNA ligase 4 [mouse-ipi-250309-contam.fasta] Tax_Id=10090 Gene_Symbol=Lig4 DNA ligase 4 ENSMUSG00000049717 IPI00225019 [IPIxENS.MOUSE_plus_REVERSE.fasta] IPI:IPI00225019.3\|SWISS-PROT:Q8BTF7\|TREMBL:Q8BTF5\|ENSEMBL:ENSMUSP00000093130\|REFSEQ:NP_795927 Tax_Id=10090 Gene_Symbol=Lig4 DNA ligase 4 [ipi.MOUSE.fasta.20090209] DNA ligase 4 OS=Mus musculus GN=Lig4 [011711_HMR.fasta]
Organism:	Mus musculus
Length:	911 amino acids
Gene Ontology:
Cellular Component:	nucleus [UNKNOWN] DNA-dependent protein kinase-DNA ligase 4 complex [UNKNOWN][IDA] intracellular [IEA]
Biological Process:	cell proliferation [IMP] DNA repair [IMP] DNA replication [IEA] DNA ligation [UNKNOWN][IDA][IMP] auxin biosynthetic process [IEA] double-strand break repair via nonhomologous end joining [IMP] negative regulation of neuron apoptosis [IGI][IMP] double-strand break repair [IGI][IMP] cell division [IEA] DNA ligation involved in DNA repair [IMP] DNA ligation involved in DNA recombination [IMP] in utero embryonic development [IMP] positive regulation of fibroblast proliferation [IMP] somatic stem cell maintenance [IMP] response to gamma radiation [IMP] neuron apoptosis [IGI] response to ionizing radiation [IMP] isotype switching [IMP] V(D)J recombination [IDA][IMP] T cell differentiation in the thymus [IMP] T cell receptor V(D)J recombination [IMP] immunoglobulin V(D)J recombination [IMP] DNA recombination [IEA] response to DNA damage stimulus [IEA] cell cycle [IEA] central nervous system development [IGI][IMP] chromosome organization [IGI] pro-B cell differentiation [IMP] positive regulation of neurogenesis [IMP]
Molecular Function:	nucleotide binding [IEA] DNA binding [UNKNOWN] ATP binding [UNKNOWN][IDA] DNA ligase (ATP) activity [UNKNOWN][IDA] metal ion binding [IEA] ligase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASSQTSQTV AAHVPFADLC STLERIQKGK DRAEKIRHFK EFLDSWRKFH DALHKNRKDV  60
   61 TDSFYPAMRL ILPQLERERM AYGIKETMLA KLYIELLNLP REGKDAQKLL NYRTPSGART 120
  121 DAGDFAMIAY FVLKPRCLQK GSLTIQQVNE LLDLVASNNS GKKKDLVKKS LLQLITQSSA 180
  181 LEQKWLIRMI IKDLKLGISQ QTIFSIFHND AVELHNVTTD LEKVCRQLHD PSVGLSDISI 240
  241 TLFSAFKPML AAVADVERVE KDMKQQSLYI ETKLDGERMQ MHKDGALYRY FSRNGYNYTD 300
  301 QFGESPQEGS LTPFIHNAFG TDVQACILDG EMMAYNPTTQ TFMQKGVKFD IKRMVEDSGL 360
  361 QTCYSVFDVL MVNKKKLGRE TLRKRYEILS STFTPIQGRI EIVQKTQAHT KKEVVDALND 420
  421 AIDKREEGIM VKHPLSIYKP DKRGEGWLKI KPEYVSGLMD ELDVLIVGGY WGKGSRGGMM 480
  481 SHFLCAVAET PPPGDRPSVF HTLCRVGSGY TMKELYDLGL KLAKYWKPFH KKSPPSSILC 540
  541 GTEKPEVYIE PQNSVIVQIK AAEIVPSDMY KTGSTLRFPR IEKIRDDKEW HECMTLGDLE 600
  601 QLRGKASGKL ATKHLHVGDD DEPREKRRKP ISKTKKAIRI IEHLKAPNLS NVNKVSNVFE 660
  661 DVEFCVMSGL DGYPKADLEN RIAEFGGYIV QNPGPDTYCV IAGSENVRVK NIISSDKNDV 720
  721 VKPEWLLECF KTKTCVPWQP RFMIHMCPST KQHFAREYDC YGDSYFVDTD LDQLKEVFLG 780
  781 IKPSEQQTPE EMAPVIADLE CRYSWDHSPL SMFRHYTIYL DLYAVINDLS SRIEATRLGI 840
  841 TALELRFHGA KVVSCLSEGV SHVIIGEDQR RVTDFKIFRR MLKKKFKILQ ESWVSDSVDK 900
  901 GELQEENQYL L

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.96

Protein Overview: DNLI4_MOUSE, DNL...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: