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Protein Overview: FOLH1

General Information:
Name(s) found: FOLH1 [HGNC (HUGO)]
Description(s) found:
Found 40 descriptions.
SHOW ALL
  • folate hydrolase (prostate-specific membrane antigen) 1 [HGNC (HUGO)]
    • Organism: Homo sapiens
    Length: 750 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWNLLHETDS AVATARRPRW LCAGALVLAG GFFLLGFLFG WFIKSSNEAT NITPKHNMKA  60
   61 FLDELKAENI KKFLYNFTQI PHLAGTEQNF QLAKQIQSQW KEFGLDSVEL AHYDVLLSYP 120
  121 NKTHPNYISI INEDGNEIFN TSLFEPPPPG YENVSDIVPP FSAFSPQGMP EGDLVYVNYA 180
  181 RTEDFFKLER DMKINCSGKI VIARYGKVFR GNKVKNAQLA GAKGVILYSD PADYFAPGVK 240
  241 SYPDGWNLPG GGVQRGNILN LNGAGDPLTP GYPANEYAYR RGIAEAVGLP SIPVHPIGYY 300
  301 DAQKLLEKMG GSAPPDSSWR GSLKVPYNVG PGFTGNFSTQ KVKMHIHSTN EVTRIYNVIG 360
  361 TLRGAVEPDR YVILGGHRDS WVFGGIDPQS GAAVVHEIVR SFGTLKKEGW RPRRTILFAS 420
  421 WDAEEFGLLG STEWAEENSR LLQERGVAYI NADSSIEGNY TLRVDCTPLM YSLVHNLTKE 480
  481 LKSPDEGFEG KSLYESWTKK SPSPEFSGMP RISKLGSGND FEVFFQRLGI ASGRARYTKN 540
  541 WETNKFSGYP LYHSVYETYE LVEKFYDPMF KYHLTVAQVR GGMVFELANS IVLPFDCRDY 600
  601 AVVLRKYADK IYSISMKHPQ EMKTYSVSFD SLFSAVKNFT EIASKFSERL QDFDKSNPIV 660
  661 LRMMNDQLMF LERAFIDPLG LPDRPFYRHV IYAPSSHNKY AGESFPGIYD ALFDIESKVD 720
  721 PSKAWGEVKR QIYVAAFTVQ AAAETLSEVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..750] PSI-BLAST 1000.0 No description for 2ootA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • peptidase activity
    		•  4.786910294594 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  4.40766568731738 bayes_pls_golite062009
  • transferrin receptor activity
    		•  4.23222910697724 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  3.22550147993876 bayes_pls_golite062009
  • hydrolase activity
    		•  2.98013991489506 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.89997705780823 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.88322998065547 bayes_pls_golite062009
  • exopeptidase activity
    		•  2.85109457647548 bayes_pls_golite062009
  • metallopeptidase activity
    		•  2.76103081380105 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.68490358267624 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  2.66431152897721 bayes_pls_golite062009
  • receptor activity
    		•  2.50668975998057 bayes_pls_golite062009
  • signal transducer activity
    		•  2.43554678928141 bayes_pls_golite062009
  • molecular transducer activity
    		•  2.43554678928141 bayes_pls_golite062009
  • transition metal ion transmembrane transporter activity
    		•  2.20995944464635 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.13164513953563 bayes_pls_golite062009
  • metalloexopeptidase activity
    		•  1.76058821499096 bayes_pls_golite062009
  • transporter activity
    		•  1.41427351827978 bayes_pls_golite062009
  • catalytic activity
    		•  1.3989281287879 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.21006084747883 bayes_pls_golite062009
  • di-, tri-valent inorganic cation transmembrane transporter activity
    		•  1.20973073749196 bayes_pls_golite062009
  • iron ion transmembrane transporter activity
    		•  1.15627568837889 bayes_pls_golite062009
  • metallocarboxypeptidase activity
    		•  1.15035221474504 bayes_pls_golite062009
  • binding
    		•  1.13031326446259 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  0.982528171716301 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.928708750561725 bayes_pls_golite062009
  • endopeptidase activity
    		•  0.910234727191613 bayes_pls_golite062009
  • carboxypeptidase activity
    		•  0.891655769761122 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.750920789301107 bayes_pls_golite062009
  • DNA binding
    		•  0.629467984227905 bayes_pls_golite062009
  • serine hydrolase activity
    		•  0.596149133958797 bayes_pls_golite062009
  • serine-type peptidase activity
    		•  0.578572340123331 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.140027513499495 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.103908874877312 bayes_pls_golite062009
  • aminopeptidase activity
    		•  0.0966237570696103 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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