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Protein Overview: YPL245W

General Information:
Name(s) found: YPL245W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 454 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHGPTSKAIS RNVRSVKRPR RAPRPVVSTQ AMNKLSNVTL SAEQEKLRER VLSFMRSNLS  60
   61 QYKSDWKHPA MFVIQGDAGT GKSVILNSLF NEIQKLSQFS PSSEDILHGT HNYLVVNHPE 120
  121 MLKLYIRISD SFKYISKSSL ERPTSLINNL QKRKVMADVV IVDEAHLLAT SKDAFKRFYG 180
  181 ENHLKDLMSL CKVLVLVYDD KQALRMGSYW DEGSNNGATL KDFYNEIPPK SRDWYTLKQQ 240
  241 FRVAAPQNVL NWIDQISVAG KIPPIESVLS KGNADCADDK IKNFDFKIWD DCGAMYEAIK 300
  301 EKDRQYGQCR MLSTYDFPYR LDGKDYYVEC GDNFKVRWDR YTPREVTPWS ERCDTIDEVG 360
  361 SVYTIQGFDL NYAGVILGRS IGYDAANDCI KLRPELYDDR AGFTKKKNIH NAEDVKQKII 420
  421 MNSINVLLTR GVRGLYVYAY DPELRERLLR PSKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DCS1 DCS2 YPL245W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPL245W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..214] MSA 2.020997 View MSA. No confident structure predictions are available.
    2 View Details [215..279] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [280..402] MSA 1.020992 View MSA. No confident structure predictions are available.
    4 View Details [403..454] deduced N/A Confident ab initio structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.20306526252293 bayes_pls_golite062009
  • catalytic activity
    		•  0.176212702885001 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.144577483271964 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.139313036912271 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.129169762987777 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.127860910307335 bayes_pls_golite062009
  • hydrolase activity
    		•  0.0424527315683166 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle