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Protein Overview: MUK1

General Information:
Name(s) found: MUK1 / YPL070W [SGD]
Description(s) found:
Found 26 descriptions.
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  • Cytoplasmic protein of unknown function containing a Vps9 domain; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 612 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: regulation of transcription [RCALink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MARQLFTPPI TNPRFDPNQS IRESYKNTTG GMQFQQNLHE DQNDNERSSC DGDENSTTGE  60
   61 RLENNKSPIL TKQEIDEALN TVTNLPPELS KLIDIFIDDL KQPKYVRPLS VLQLSSLFQS 120
  121 FYIKFDKASF QHVSSANNNG YYFSGGGSSS FLAAKETLSS GLSGIFGRSR SSSGNSLMRP 180
  181 RRSSSLFSNE SISNSTNATQ MLSPEEIKKQ LKINELNNMK IEKYMELCER DVFKKILIVG 240
  241 TSVSSPNKMK TFKPHQLQTF KVGNLFRNSV EFTEYNKLLN EKILCLSKLS TMNKINLIKF 300
  301 LSLNNGIDPE PKFEEIKDIL YEFTYHSISP CEKIKALLKL HEIMTYSQEM SNDDYLSLLI 360
  361 YYIITIVPRD IFLNAEFIRL FRYKKKLVET ESFALTNLEA ALVFVEGLTK NDFSNELQDK 420
  421 LTVNESKILE NSISSRVSLP SKTAIMHKNN GNNGSNLGDI VTPTIQRPDV TRSNSYDGFR 480
  481 TVFDSSLKNI IGKIRSYTPP HPNNTSNNNL HSSNNLNIPR SSSQLSMELS NRDTTEMSRD 540
  541 GSRSTSSSSR SSASLEHGNR EFTGDLTVTA SINGADKKEF QKSWKKYKGY KFEDLTICEL 600
  601 RDLFEIYQKM MQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) MUK1 VPS17 VPS5
    View Details Krogan NJ, et al. (2006) MIA40 MUK1 PEP8 VPS17 VPS29 VPS35 VPS5

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen CDC28 MUK1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data MUK1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..159] MSA 1.020962 View MSA. No confident structure predictions are available.
    2 View Details [160..268] deduced N/A No confident structure predictions are available.
    3 View Details [269..461] Pfam 38.769551 Vacuolar sorting protein 9 (VPS9) domain No confident structure predictions are available.
    4 View Details [462..612] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.510165328291727 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle