Protein Overview: SCP1

General Information:
Name(s) found:	SCP1 / YOR367W [SGD]
Description(s) found: Found 25 descriptions. SHOW ALL	Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin [SGD]
Organism:	Saccharomyces cerevisiae
Length:	200 amino acids
Gene Ontology:
Cellular Component:	actin cortical patch [IDA]
Biological Process:	actin filament organization [IDA] chronological cell aging [IGI][IMP]
Molecular Function:	actin filament binding [IDA] protein binding, bridging [IDA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYDKKADVT SLDEDLRQLR ESKFSPEAIQ NIKIWVYKSV LKEIAPPGDL LECLKDGTVL  60
   61 CKLANILYEA DTGEANHISW KSSKMPFVQM DQISQFLSFS RKYGVPEDEL FQTIDLFEKK 120
  121 DPAIVFQTLK SLSRYANKKH TDRFPVLGPQ LSTKKPRPPV KSKPKHLQDG TGWSTFEYGY 180
  181 MKGASQATEG VVLGQRRDIV

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		ABP1 ARP3 HXT7 SCP1 SPS1 TUP1 YSC84
View Details	Qiu et al. (2008)		AIP1 ARP2 BBC1 BNI1 BSP1 BUD6 CAP1 CAP2 COF1 CRN1 END3 ENT1 ENT2 IQG1 MYO2 PAN1 PFY1 RVS161 SAC6 SCP1 SLA1 SLA2 SRV2 TPM1 TWF1 VRP1

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	UBC7	SCP1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	SCP1 and SAC6	Huh WK, et al. (2003)
View Data	SCP1	Huh WK, et al. (2003)

Protein Structure Data

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Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..200]	PSI-BLAST	86.457575	Calponin

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2