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Protein Overview: SCP1

General Information:
Name(s) found: SCP1 / YOR367W [SGD]
Description(s) found:
Found 25 descriptions.
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  • Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 200 amino acids

    Gene Ontology:
    Cellular Component: actin cortical patch [IDALink to PubMed article]
    Biological Process: actin filament organization [IDALink to PubMed article]
    chronological cell aging [IGILink to PubMed article][IMPLink to PubMed article]
    Molecular Function: actin filament binding [IDALink to PubMed article]
    protein binding, bridging [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSYDKKADVT SLDEDLRQLR ESKFSPEAIQ NIKIWVYKSV LKEIAPPGDL LECLKDGTVL  60
   61 CKLANILYEA DTGEANHISW KSSKMPFVQM DQISQFLSFS RKYGVPEDEL FQTIDLFEKK 120
  121 DPAIVFQTLK SLSRYANKKH TDRFPVLGPQ LSTKKPRPPV KSKPKHLQDG TGWSTFEYGY 180
  181 MKGASQATEG VVLGQRRDIV

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ABP1 ARP3 HXT7 SCP1 SPS1 TUP1 YSC84
    View Details Qiu et al. (2008) AIP1 ARP2 BBC1 BNI1 BSP1 BUD6 CAP1 CAP2 COF1 CRN1 END3 ENT1 ENT2 IQG1 MYO2 PAN1 PFY1 RVS161 SAC6 SCP1 SLA1 SLA2 SRV2 TPM1 TWF1 VRP1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data SCP1 and SAC6 Huh WK, et al. (2003)
    View Data SCP1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..200] PSI-BLAST 86.457575 Calponin


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle