YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: YPK9

General Information:
Name(s) found: YPK9 / YOR291W [SGD]
Description(s) found:
SHOW ONLY BEST
  • gi|6324865|ref|NP_014934.1| Putative protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; YOR291W is not an essential protein; Yor291wp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|2493012|sp|Q12697.1|ATC9_YEAST RecName: Full=Probable cation-transporting ATPase 2 [NCBI NR]
  • pir||S67195 probable membrane protein YOR291w - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|1420646|emb|CAA99518.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • Probable cation-transporting ATPase 2 OS=Saccharomyces cerevisiae GN=YOR291W PE=1 SV=1 [Swiss-Prot]
  • Putative cation translocating ATPases [mips]
  • Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome [SGD]
  • (Q12697) Probable cation-transporting ATPase 2 (EC 3.6.3.-) [4932.FASTACCERV.txt]
  • Chr XV from 861172-865590 [hmr_yeast5_DM3-1_pombe.fasta]
  • Chr XV from 861171-865589 [yeastorf3.fasta]
  • YOR291W, Chr XV from 861171-865589 [yeast_orfs2]
  • YOR291W SGDID:S0005817, Chr XV from 861172-865590, Uncharacterized ORF [yeastflysequest.fasta]
  • Yor291wp [Saccharomyces cerevisiae]gi|1420646|emb|CAA99518.1| unnamed protein product [Saccharomyces cerevisiae]gi|2493012|sp|Q12697|ATC9_YEAST Probable cation-transporting ATPase 2gi|2132937|pir||S67195 probable membrane protein YOR291w - yeast (Sacch [nrdb_11152004_Chlamydomonas]
  • YOR291W SGDID:S000005817, Chr XV from 861172-865590, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • YOR291W SGDID:S000005817, Chr XV from 861174-865592, Uncharacterized ORF, "Hypothetical protein" [yeast-contam.fasta]
  • YOR291W SGDID:S000005817, Chr XV from 861174-865592, Uncharacterized ORF, "Putative protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; YOR291W is not an essential protein" [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861174-865592, Verified ORF, "Vacuolar protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; null mutant is hypersensitive to manganese; homolog of human ATP13A2 (PARK9), mutations [yeast-200209-contam.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861174-865592, Verified ORF, "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with [SGD_S-cerevisiae_na_05-08-2009_con_reversed.fasta]
  • Probable cation-transporting ATPase 2 [nr-271106-contam.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • hypothetical protein; Yor291wp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861174-865592, Verified ORF, "Vacuolar protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; null mutant is hypersensitive to manganese; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease 9" [yeast-bovrabprots.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861174-865592, Verified ORF, "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor?Rakeb syndrome" [scerevisihumanrev.fasta]
  • [chemostatdb.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861175-865593, Genome Release 64-1-1, Verified ORF, "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome" [yeast-030211-contam.fasta]
  • YPK9 SGDID:S000005817, Chr XV from 861175-865593, Genome Release 64-2-1, Verified ORF, "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome" [20141208_orf_trans.fasta]
  • YOR291W SGDID:S000005817, Chr XV from 861175-865593, Genome Release 64-1-1, Verified ORF, "Vacuolar protein with a possible role in sequestering heavy metals; has similarity to the type V P-type ATPase Spf1p; homolog of human ATP13A2 (PARK9), mutations in which are associated with Parkinson disease and Kufor-Rakeb syndrome" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
    • Organism: Saccharomyces cerevisiae
    Length: 1472 amino acids

    Gene Ontology:
    Cellular Component: membrane [ISSLink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIPSSNQIQ HGQRSERNRR MPRASFSSTA TTSTAATLTS AMVLDQNNSE PYAGATFEAV  60
   61 PSSIVSFHHP HSFQSSNLPS PHSSGNLEQR GRRLTESEPL VLSSAEQSRS SSRNPSHFRF 120
  121 FTQEQISNAE GASTLENTDY DMAWDATPAY EQDRIYGTGL SSRRSSIRSF SRASSLSNAK 180
  181 SYGSFSKRGR SGSRAPQRLG ENSDTGFVYH SATHSSSSLS RYTTRERIPI ELESQTDEIL 240
  241 EDESSTHSLE SSDSRRSASE NNRGSFSGHD DVHNQHSEYL KPDYHEKFYP QYAPNLHYQR 300
  301 FYIAEEDLVI GIAAYQTSKF WYIIYNLCCF LTFGLVYLLT RWLPHLKVKL YGVKVPLAKA 360
  361 EWVVIENEFG EFVIQPIDRQ WYNRPLSTVL PFENYPNPSY EPNDINLSHH HANEINPNVP 420
  421 ILITFEYRYI KFIYSPLDDL FKTNNNWIDP DWVDLSTVSN GLTKGVQEDR ELAFGKNQIN 480
  481 LRMKTTSEIL FNEVLHPFYV FQVFSIILWG IDEYYYYAAC IFLISVLSIF DSLNEQKKVS 540
  541 RNLAEMSHFH CDVRVLRDKF WTTISSSELV PGDIYEVSDP NITILPCDSI LLSSDCIVNE 600
  601 SMLTGESVPV SKFPATEETM YQLCDDFQST QISSFVSKSF LYNGTNIIRA RIAPGQTAAL 660
  661 AMVVRTGFST TKGSLVRSMV FPKPTGFKFY RDSFKYIGFM SLIAIFGFCV SCVQFIKLGL 720
  721 DKKTMILRAL DIITIVVPPA LPATLTIGTN FALSRLKEKG IFCISPTRLN ISGKIDVMCF 780
  781 DKTGTLTEDG LDVLGVQISE PNGVRGQKFG ELLSDIRQVF PKFSLNDCSS PLDFKSRNFF 840
  841 MSLLTCHSLR SVDGNLLGDP LDFKMFQFTG WSFEEDFQKR AFHSLYEGRH EDDVFPENSE 900
  901 IIPAVVHPDS NNRENTFTDN DPHNFLGVVR SFEFLSELRR MSVIVKTNND DVYWSFTKGA 960
  961 PEVISEICNK STLPADFEEV LRCYTHNGYR VIACAGKTLP KRTWLYSQKV SREEVESNLE1020
 1021 FLGFIIFQNK LKKETSETLK SLQDANIRTI MCTGDNILTA ISVGREAGLI QCSRVYVPSI1080
 1081 NDTPLHGEPV IVWRDVNEPD KILDTKTLKP VKLGNNSVES LRECNYTLAV SGDVFRLLFR1140
 1141 DENEIPEEYL NEILLNSSIY ARMSPDEKHE LMIQLQKLDY TVGFCGDGAN DCGALKAADV1200
 1201 GISLSEAEAS VAAPFTSKIF NISCVLDVIR EGRAALVTSF ACFQYMSLYS AIQFITITIL1260
 1261 YSRGSNLGDF QFLYIDLLLI VPIAICMSWS KSYEKIDKKR PSANLVSPKI LVPLLISVFL1320
 1321 VFLFQFIPWI IVQKMSWYIK PIVGGDDAVQ SSDNTVLFFV SNFQYILTAI VLSVGPPYRE1380
 1381 PMSKNFEFIV DITVSIGASL LLMTLDTESY LGKMLQLTPI SNSFTMFIIV WVILNYYAQL1440
 1441 YIPPSIKGWL KKKKSSKKYK LLIQEEMKLK EV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run ZDS1 Sample 2- cpn2 from june 2005 McCusker D, et al (2007)
    View Run VAM3 sample: hx2 Hao Xu, et al. (2010)
    View Run VAM3 sample: hx3 Hao Xu, et al. (2010)
    View Run VAM3 sample: hx4 Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX11 - both fusion and trans-SNARE complex formation take place. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX12 - trans-SNARE complex formation and fusion are inhibited (control). Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX13 - trans-SNARE complex forms but fusion is blocked. Hao Xu, et al. (2010)
    View Run VAM3 Sample: HX14 - mixture in detergent (control). Hao Xu, et al. (2010)
    View Run VAM3 hx21: both fusion and trans-SNARE complex formation take place. Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run VAM3 hx23: mixture in detergent (control) Investigating Vam3p, Nyv1p and their partners in trans-SNARE complex Hao Xu, et al. (2010)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data YPK9 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] deduced N/A No confident structure predictions are available.
    2 View Details [415..480]
    [552..683]    		 PSI-BLAST 1063.0103 Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
    3 View Details [481..541]
    [684..748]
    [1235..1472]    		 PSI-BLAST 1063.0103 Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
    4 View Details [542..551]
    [749..788]
    [1031..1234]    		 PSI-BLAST 1063.0103 Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
    5 View Details [789..1030] PSI-BLAST 1063.0103 Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle