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Protein Overview: RIM20

General Information:
Name(s) found: RIM20 / YOR275C [SGD]
Description(s) found:
Found 30 descriptions.
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  • Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 661 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: proteolysis [IMPLink to PubMed article]
    protein processing [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]
    invasive growth in response to glucose limitation [IMPLink to PubMed article]
    sporulation resulting in formation of a cellular spore [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELLAIPLK RTLEVDFATE LSKLIDTTSF QTASFFQSDI LKVVDARNNA IAPDISIDGL  60
   61 SALKEYYVIL LQLEKKFPNN QIEFTWFQTL SQKSRGTSQY SLQWEKLTII YNIGCMYSLL 120
  121 ALNSNNDAAE SLKTSCLYFQ NAAGCFKHVL DHQKNLETIP VVDDATLNAL TSLMLAQAQE 180
  181 CFWFKAVQDK HKDSLIAKLS QQIVDFYCEA INDAQRGKLI RSDWINHLKA KKAYFSAVTY 240
  241 YRIALSFNEK KQFGNVVKAL QMGLQFINES TLSSQAKFKT VVESSLKEAQ RDNEFIYLQE 300
  301 VPSELPSIKP ALMVKPSSSA TLLPSIKKDE TLFKDLIPIE VMEYCTAYNE RQDEYVEQRV 360
  361 TNPLASLNKL LKESLTTFQI PQGLTKVSEA ELSHYQASLN NLLINNKNVQ VQLDNIEQIL 420
  421 NEEAFTDNQL RLKHGTLNWT LPESSTTNTA YYEKLKKLRG YLDEGSAIDK QTNELFQSID 480
  481 KNLIGSEIRL PESNDPLTNK IKMIIQERND YIDRTRRKSS EYRILPKIIT SYKKNGTVDF 540
  541 EPIFIGHLKY FDEDLRYVNS TKEENIKLIE EVNLSKKNNP GRSGIEPKKM VRIDPRELYI 600
  601 EDLRYSFKLL DEVKENLSAG TAFYENLITS TSNLYNEVQE YDTARRAEKA RLDKSLTFED 660
  661 Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run RLF2 identification data - first search in cascade Green EM, et al (2005)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data RIM20 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..148] Pfam 64.853872 BRO1-like domain No confident structure predictions are available.
    2 View Details [149..468] PSI-BLAST 25.221849 Heavy meromyosin subfragment
    3 View Details [469..661] PSI-BLAST 9.154902 Tropomyosin


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle