YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: MGM1

General Information:
Name(s) found: MGM1 / YOR211C [SGD]
Description(s) found:
Found 14 descriptions.
SHOW ALL
  • Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 902 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial intermembrane space [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed article]
    Biological Process: mitochondrial fusion [IMPLink to PubMed article][IPILink to PubMed article]
    mitochondrion organization [IMPLink to PubMed article][TASLink to PubMed article]
    mitochondrial genome maintenance [IMPLink to PubMed article]
    Molecular Function: GTPase activity [TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSTSLRAI PRVANYNTLV RMNASPVRLL ILRRQLATHP AILYSSPYIK SPLVHLHSRM  60
   61 SNVHRSAHAN ALSFVITRRS ISHFPKIISK IIRLPIYVGG GMAAAGSYIA YKMEEASSFT 120
  121 KDKLDRIKDL GESMKEKFNK MFSGDKSQDG GHGNDGTVPT ATLIAATSLD DDESKRQGDP 180
  181 KDDDDEDDDD EDDENDSVDT TQDEMLNLTK QMIEIRTILN KVDSSSAHLT LPSIVVIGSQ 240
  241 SSGKSSVLES IVGREFLPKG SNMVTRRPIE LTLVNTPNSN NVTADFPSMR LYNIKDFKEV 300
  301 KRMLMELNMA VPTSEAVSEE PIQLTIKSSR VPDLSLVDLP GYIQVEAADQ PIELKTKIRD 360
  361 LCEKYLTAPN IILAISAADV DLANSSALKA SKAADPKGLR TIGVITKLDL VDPEKARSIL 420
  421 NNKKYPLSMG YVGVITKTPS SINRKHLGLF GEAPSSSLSG IFSKGQHGQS SGEENTNGLK 480
  481 QIVSHQFEKA YFKENKKYFT NCQVSTKKLR EKLIKILEIS MSNALEPTST LIQQELDDTS 540
  541 YLFKVEFNDR HLTPKSYLLN NIDVLKLGIK EFQEKFHRNE LKSILRAELD QKVLDVLATR 600
  601 YWKDDNLQDL SSSKLESDTD MLYWHKKLEL ASSGLTKMGI GRLSTMLTTN AILKELDNIL 660
  661 ESTQLKNHEL IKDLVSNTAI NVLNSKYYST ADQVENCIKP FKYEIDLEER DWSLARQHSI 720
  721 NLIKEELRQC NSRYQAIKNA VGSKKLANVM GYLENESNLQ KETLGMSKLL LERGSEAIFL 780
  781 DKRCKVLSFR LKMLKNKCHS TIEKDRCPEV FLSAVSDKLT STAVLFLNVE LLSDFFYNFP 840
  841 IELDRRLTLL GDEQVEMFAK EDPKISRHIE LQKRKELLEL ALEKIDSILV FKKSYKGVSK 900
  901 NL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Qiu et al. (2008) FZO1 MGM1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 No Comments Schneider, DA, et al. (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #13 Mitotic Prep2-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #12 Mitotic Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #11 Mitotic Prep1-TiO2 enriched, new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..184] MSA 1.049939 View MSA. No confident structure predictions are available.
    2 View Details [185..510] PSI-BLAST 506.529817 Dynamin G domain
    3 View Details [511..902] ORFEUS 9.46 Clathrin heavy chain proximal leg segment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.0681607836408 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  1.737153612961 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  1.66717045339473 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  1.64692747234601 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  1.64482911944641 bayes_pls_golite062009
  • hydrolase activity
    		•  1.16405290417756 bayes_pls_golite062009
  • motor activity
    		•  0.50661339105747 bayes_pls_golite062009
  • purine nucleotide binding
    		•  0.370109410491501 bayes_pls_golite062009
  • nucleotide binding
    		•  0.367488441096941 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  0.348507955395744 bayes_pls_golite062009
  • ribonucleotide binding
    		•  0.348454114797054 bayes_pls_golite062009
  • protein binding
    		•  0.193768631623192 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  2.38363524631144 bayes_pls_golite062009
  • protein binding
    		•  1.63424405980235 bayes_pls_golite062009
  • protein transporter activity
    		•  0.47381617541112 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle