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Protein Overview: YOL057W

General Information:
Name(s) found: YOL057W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Dipeptidyl-peptidase III; cleaves dipeptides from the amino terminus of target proteins; highly active on synthetic substrate Arg-Arg-2-naphthylamide; mammalian ortholog may be a biomarker for some cancers [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 711 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSHFFADHDA PLSMLSVKTE YFPQLTDKEQ KYAHFMSKAS HAGSRVVMRQ VSHESEPIFD  60
   61 LILAIHSKLN GKYPEDDITQ KQQTGLYLEY VSQFLSNLGN FKSFGDTKFI PRCEVKFFKQ 120
  121 LLELAKINPC SSPLTLSPVD VNHEFTSHHL FSTINELIDI GIYHVEEKAA LLGFPSQGYT 180
  181 SAYYLGLPVT PEDMALLKEQ LFAELAILPE NTRINKVGEN SFQIWVASEN VKNQITETYP 240
  241 SGQITLSNAV TKVEFIFGDH SREMRLVASY LKEAQKFAAN DTQKAMLQEY INHFVTGSSQ 300
  301 AHKEAQKLWV KDISPVIETN IGFIETYREP SGIIGEFESL VAIQNKERTA KFSSLVNNAE 360
  361 EFISLLPWSK DYEKPIFNPP DFTSLEVLTF TGSGIPAGIN IPNYDDVRLK IGFKNVSLGN 420
  421 ILSAAAKSSS KHPPSFISQE DRPIFEKYQS DSFEVQVGIH ELLGHGSGKL LTEFTDGFNF 480
  481 DKENPPLGLD GKPVSTYYKV GETWGSKFGQ LAGPFEECRA EVIAMFLLTN KKILDIFGFH 540
  541 DVESQDKVIY AGYLQMARAG LLALEYWNPK TGKWGQPHMQ ARFSIMKTFM KHSTDKNFLK 600
  601 LEMNSTNDDF AIKLDKSLIK TAGHECVKDY LKHLHVYKCS GDVEQGSKYF IDRSTVTPDL 660
  661 ASLRDIVLSK RLPRRQFIQS NSYIDDNNKV TLKEYDETPQ GMLQSFLDRE L

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) BPH1 YOL057W

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run CAB4 No Comments Hazbun TR, et al. (2003)
    View Run BIR1 sample bir 1 from feb 2005 Sandall S, et all (2006)
    View Run MLP2 #31 Asynchronous Prep (Protease cleavage) Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data YOL057W Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..130] MSA 1.007966 View MSA. No confident structure predictions are available.
    2 View Details [131..711] Pfam 1000.0 Peptidase family M49 No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle