Protein Overview: YNL311C

General Information:
Name(s) found:	YNL311C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|633671\|emb\|CAA86384.1\| NO376 [Saccharomyces cerevisiae] [NCBI NR] gi\|6324018\|ref\|NP_014088.1\| Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein cat [NCBI NR] gi\|1302415\|emb\|CAA96240.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] gi\|1176587\|sp\|P42843.1\|YN51_YEAST RecName: Full=F-box protein YNL311C [NCBI NR] pir\|\|S51300 probable membrane protein YNL311c - yeast (Saccharomyces cerevisiae) [NCBI NR] F-box protein YNL311C OS=Saccharomyces cerevisiae GN=YNL311C PE=1 SV=1 [Swiss-Prot] SKP2 Putative member of ubiquitin ligase complex [mips] Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein catabolism [SGD] Chr XIV from 49396-51687, reverse complement [yeastorf3.fasta] Chr XIV from 51687-49396, reverse complement [yeastorf5.fasta] (P42843) Hypothetical 88.9 kDa protein in RFA2-STB1 intergenic region [4932.FASTACCERV.txt] YNL311C, Chr XIV from 49396-51687, reverse complement [yeast_orfs2] YNL311C SGDID:S0005255, Chr XIV from 51687-49396, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] F-box protein [Saccharomyces cerevisiae]gi\|1302415\|emb\|CAA96240.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|1077430\|pir\|\|S51300 probable membrane protein YNL311c - yeast (Saccharomyces cerevisiae)gi\|1176587\|sp\|P42843\|YN51_YEAST Hypothetical [nrdb_11152004_Chlamydomonas] YNL311C SGDID:S000005255, Chr XIV from 51687-49396, reverse complement, Uncharacterized ORF, "F-box protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YNL311C SGDID:S000005255, Chr XIV from 51687-49396, reverse complement, Uncharacterized ORF, "Putative F-box protein; analysis of integrated high-throughput datasets predicts an involvement in ubiquitin-dependent protein catabolism" [yeast-contam.fasta] YNL311C SGDID:S000005255, Chr XIV from 51687-49396, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datas [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Putative F-box protein; analysis of integrated high-throughput datasets predicts an involvement in ubiquitin-dependent protein catabolism; Skp2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] NO376 [Saccharomyces cerevisiae] [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Uncharacterized F-box protein YNL311C [nr-271106-contam.fasta] YNL311C SGDID:S000005255, Chr XIV from 51687-49396, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein catabolism" [yeast-bovrabprots.fasta] [chemostatdb.fasta] SKP2 SGDID:S000005255, Chr XIV from 51688-49397, Genome Release 64-1-1, reverse complement, Verified ORF, "F-box protein of unknown function predicted to be part of an SCF ubiquitin protease complex; involved in regulating protein levels of sulfur metabolism enzymes; may interact with ribosomes, based on co-purification experiments" [yeast-030211-contam.fasta] SKP2 SGDID:S000005255, Chr XIV from 51688-49397, Genome Release 64-2-1, reverse complement, Verified ORF, "F-box protein of unknown function; predicted to be part of an SCF ubiquitin protease complex; involved in regulating protein levels of sulfur metabolism enzymes; may interact with ribosomes, based on co-purification experiments" [20141208_orf_trans.fasta] YNL311C SGDID:S000005255, Chr XIV from 51688-49397, Genome Release 64-1-1, reverse complement, Verified ORF, "F-box protein of unknown function predicted to be part of an SCF ubiquitin protease complex; involved in regulating protein levels of sulfur metabolism enzymes; may interact with ribosomes, based on co-purification experiments" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	763 amino acids
Gene Ontology:
Cellular Component:	ubiquitin ligase complex [ISS] ribosome [IDA]
Biological Process:	ubiquitin-dependent protein catabolic process [ISS]
Molecular Function:	protein binding [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRLQLFGRS KYFSLVSSAA KEEEEEEEGC ADAKSLLHST SHDIKSRSLR FNDKSSLMCL  60
   61 PTKVLLLILR TLDFNTLVTL CQVNSRFYNL ITNEFLFQNV ILDSKLSLLK FNALIHSEFH 120
  121 TSNIVTHSGD CSTQSRSQNA RFLVRSIEFK NPQSQDSLLK YSKFYNKSGQ DSIIAGSYKL 180
  181 DSYDKDVKKL NNIRLNDETP IITSERIKLL DKLESNYFHY TYIELMLDII DYLPNLTRVI 240
  241 LSDVEPNFKI PLWYSVFNDG SRDFFKKIIK GQQSITNEDL RTFQLSKKFV KEYESKYYSL 300
  301 PRLKILEIKA NNKRQRTFNR QRHHQKLVLR PSLFCCFGII NELKLENVTI DTESLDTPME 360
  361 FLPLFLKNED NELYSLQSPI TALTLDSCDV VPGNGILRLF HSYFKMVKHL SLLKINSKFD 420
  421 LLLCSCFPSL SNLTIDCNSK CFTNEQVVGE SYYFQQRSLD TEDDFDDCNS MTETLFEAPS 480
  481 DSKIITPPPT SSVVLSLNLN YISRTTGNDV SNNPSPDNNK KPAMLTAAQL QNFQRQRIPE 540
  541 FHSFYHYYRL LWERLPSKNI SINVINIPFT NVYPLSPLSF WEHLARTITS VDETDEDVGD 600
  601 ENDQETLIGY ENNSIRDNIP NANAVPNLST VMSPESDIHH TYYWNNSVRR CLRDSLIKLK 660
  661 NRTIEYRDLD VEEFLQNVTL ENFFNDFQDP ENFKDIPNIN LWCFLRNLSK FKAVKIRMLR 720
  721 HFSLCTPRTR YDWELLLKPV LRVNVPIEVR DKDGFVLYSY GQK

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Ho Y, et al. (2002)		DMA1 DMA2 ERG1 RPT2 RPT4 RVB1 SKP1 STI1 UBI4 YNL311C
View Details	Qiu et al. (2008)		UFO1 YLR224W YNL311C

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	CEP3	sample cbf3 from feb 2005	Sandall S, et all (2006)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	YNL311C	LUC7	1	Unpublished Fields Lab Data
View Screen	YNL311C	YHL037C	1	Unpublished Fields Lab Data
View Screen	YNL311C	ATG16	1	Unpublished Fields Lab Data
View Screen	YNL311C	YPL191C	1	Unpublished Fields Lab Data
View Screen	YNL311C	YPL247C	1	Unpublished Fields Lab Data
View Screen	RAD1	YNL311C	1	Unpublished Fields Lab Data
View Screen	KAP104	YNL311C	1	Unpublished Fields Lab Data
View Screen	SKP1	YNL311C	1	Unpublished Fields Lab Data
View Screen	DMC1	YNL311C	1	Unpublished Fields Lab Data
View Screen	CUS1	YNL311C	1	Unpublished Fields Lab Data
View Screen	YNL311C	YBR284W	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	YNL311C	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..128]	Pfam	4.585027	F-box domain No confident structure predictions are available.
2	View Details	[129..763]	deduced	N/A	No confident structure predictions are available.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.93

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2