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Protein Overview: CUE1

General Information:
Name(s) found: CUE1 / YMR264W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 203 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDALink to PubMed articleLink to PubMed article]
    integral to endoplasmic reticulum membrane [IDALink to PubMed article]
    Biological Process: establishment of protein localization [IMPLink to PubMed article]
    ER-associated protein catabolic process [IMPLink to PubMed article]
    Molecular Function: protein binding [IDALink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEDSRLLITL ILVFGVIFLK KFFQSNQHPS AQRLSATGVN AHGRPQGSTQ NALRRTGRVN  60
   61 GGHPVTTQMV ETVQNLAPNL HPEQIRYSLE NTGSVEETVE RYLRGDEFSF PPGFEPSRAP 120
  121 MGANAAVDNN AAGGGEFNDP RKKNMICAEN LLDKFHVDLN EDMSNLSFKD LDIEERKRLL 180
  181 VWQARKNLET KLQSDKDLQS LLT

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CLG1 CUE1 GTR1 HAM1 HRT1 LAP3 TFP1 VMA10 VMA13 VMA2 VMA7 VMA8 XDJ1 YIG1

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YGR160W CUE1 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data CUE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] Pfam 12.744727 CUE domain No confident structure predictions are available.
    2 View Details [110..203] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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