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Protein Overview: XDJ1

General Information:
Name(s) found: XDJ1 / YLR090W [SGD]
Description(s) found:
Found 28 descriptions.
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  • Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    Biological Process: telomere maintenance [IMPLink to PubMed article]
    Molecular Function: chaperone regulator activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSDRGDRL YDVLGVTRDA TVQEIKTAYR KLALKHHPDK YVDQDSKEVN EIKFKEITAA  60
   61 YEILSDPEKK SHYDLYGDDN GAASSGGANG FGDEDFMNFF NNFFNNGSHD GNNFPGEYDA 120
  121 YEEGNSTSSK DIDIDISLTL KDLYMGKKLK FDLKRQVICI KCHGSGWKPK RKIHVTHDVE 180
  181 CESCAGKGSK ERLKRFGPGL VASQWVVCEK CNGKGKYTKR PKNPKNFCPD CAGLGLLSKK 240
  241 EIITVNVAPG HHFNDVITVK GMADEEIDKT TCGDLKFHLT EKQENLEQKQ IFLKNFDDGA 300
  301 GEDLYTSITI SLSEALTGFE KFLTKTFDDR LLTLSVKPGR VVRPGDTIKI ANEGWPILDN 360
  361 PHGRCGDLYV FVHIEFPPDN WFNEKSELLA IKTNLPSSSS CASHATVNTE DDSNLTNNET 420
  421 ISNFRIIHTD DLPEGIRPFK PEAQDSAHQK ARSSYCCIQ

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) CLG1 CUE1 GTR1 HAM1 HRT1 LAP3 TFP1 VMA10 VMA13 VMA2 VMA7 VMA8 XDJ1 YIG1

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #25 Asynchronous Prep3-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen YPI1 XDJ1 2 Hazbun TR, et al. (2003)

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data XDJ1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] PSI-BLAST 149.30103 DnaJ chaperone, N-terminal (J) domain
    2 View Details [121..238] PSI-BLAST 15.69897 Cysteine-rich domain of the chaperone protein DnaJ.
    3 View Details [239..399] PSI-BLAST 73.0 Heat shock protein 40 Sis1
    4 View Details [400..459] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • unfolded protein binding
    		•  3.04403163860617 bayes_pls_golite062009
  • heat shock protein binding
    		•  2.17994194200939 bayes_pls_golite062009
  • binding
    		•  2.03854863870179 bayes_pls_golite062009
  • chaperone binding
    		•  1.61155546076854 bayes_pls_golite062009
  • protein binding
    		•  0.912937133925792 bayes_pls_golite062009
  • Hsp70 protein binding
    		•  0.541755903922701 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.423488346839872 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.146399219759372 bayes_pls_golite062009
  • catalytic activity
    		•  0.106988907594358 bayes_pls_golite062009
  • DNA binding
    		•  0.10307408349439 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.13705208493215 bayes_pls_golite062009
  • unfolded protein binding
    		•  2.04158808514315 bayes_pls_golite062009
  • protein binding
    		•  0.882827615657312 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  0.290861970307477 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  0.290861970307477 bayes_pls_golite062009
  • catalytic activity
    		•  0.276917867171685 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  0.0964866497718595 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle