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Protein Overview: SSO2

General Information:
Name(s) found: SSO2 / YMR183C [SGD]
Description(s) found:
Found 23 descriptions.
SHOW ALL
  • Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 295 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [TASLink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    endoplasmic reticulum [IDALink to PubMed article]
    Biological Process: vesicle fusion [TASLink to PubMed article]
    Golgi to plasma membrane transport [TASLink to PubMed article]
    Molecular Function: receptor signaling protein serine/threonine kinase activity [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNANPYENN NPYAENYEMQ EDLNNAPTGH SDGSDDFVAF MNKINSINAN LSRYENIINQ  60
   61 IDAQHKDLLT QVSEEQEMEL RRSLDDYISQ ATDLQYQLKA DIKDAQRDGL HDSNKQAQAE 120
  121 NCRQKFLKLI QDYRIIDSNY KEESKEQAKR QYTIIQPEAT DEEVEAAIND VNGQQIFSQA 180
  181 LLNANRRGEA KTALAEVQAR HQELLKLEKT MAELTQLFND MEELVIEQQE NVDVIDKNVE 240
  241 DAQQDVEQGV GHTNKAVKSA RKARKNKIRC LIICFIIFAI VVVVVVVPSV VETRK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) PEP12 SEC20 SED5 SSO1 SSO2 TLG1 TLG2 UFE1
    View Details Qiu et al. (2008) PEP12 SEC20 SEC22 SEC9 SED5 SSO1 SSO2 TLG1 TLG2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RLF2 cac1: TAP-tagged Green EM, et al (2005)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SSO2 ATG7 2 Drees BL, et al. (2001)
    View Screen UBC7 SSO2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SSO2 and SNF7 Huh WK, et al. (2003)
    View Data SSO2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..144]
    [200..295]    		 PSI-BLAST 699.30103 Sso1
    2 View Details [145..199] PSI-BLAST 699.30103 Sso1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphatidic acid binding
    		•  8.51970136264329 bayes_pls_golite062009
  • SNAP receptor activity
    		•  3.50393203740159 bayes_pls_golite062009
  • binding
    		•  2.33192450173199 bayes_pls_golite062009
  • protein transporter activity
    		•  1.74973029929612 bayes_pls_golite062009
  • transporter activity
    		•  1.74189664015129 bayes_pls_golite062009
  • protein binding
    		•  1.61683263008775 bayes_pls_golite062009
  • excitatory extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • extracellular ligand-gated ion channel activity
    		•  1.54368755758216 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.49085442233849 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  1.13101548288086 bayes_pls_golite062009
  • SNARE binding
    		•  0.71459772253941 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.643064875848901 bayes_pls_golite062009
  • gated channel activity
    		•  0.621670335227137 bayes_pls_golite062009
  • ligand-gated ion channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • ligand-gated channel activity
    		•  0.41937155561589 bayes_pls_golite062009
  • extracellular-glutamate-gated ion channel activity
    		•  0.394485000881621 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.370484918396857 bayes_pls_golite062009
  • calcium channel inhibitor activity
    		•  0.24104982008887 bayes_pls_golite062009
  • channel activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • passive transmembrane transporter activity
    		•  0.0647076360772156 bayes_pls_golite062009
  • substrate-specific channel activity
    		•  0.0435980899803177 bayes_pls_golite062009
  • phospholipid binding
    		•  0.0172309833091902 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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