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Protein Overview: YKR017C

General Information:
Name(s) found: YKR017C [SGD]
Description(s) found:
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  • gi|6322869|ref|NP_012942.1| Putative protein of unknown function; contains a RING finger motif; Ykr017cp [Saccharomyces cerevisiae] [NCBI NR]
  • gi|549769|sp|P36113.1|YKZ7_YEAST RecName: Full=RING finger protein YKR017C [NCBI NR]
  • pir||S38086 hypothetical protein YKR017c - yeast (Saccharomyces cerevisiae) [NCBI NR]
  • gi|486435|emb|CAA82089.1| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR]
  • RING finger protein YKR017C OS=Saccharomyces cerevisiae GN=YKR017C PE=1 SV=1 [Swiss-Prot]
  • Protein of unknown function [mips]
  • Putative protein of unknown function; contains a RING finger motif [SGD]
  • YKR017C, Chr XI from 471332-472987, reverse complement [yeast_orfs2]
  • Chr XI from 471332-472987, reverse complement [yeastorf3.fasta]
  • Chr XI from 472987-471332, reverse complement [yeastorf5.fasta]
  • (P36113) Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region [4932.FASTACCERV.txt]
  • YKR017C SGDID:S0001725, Chr XI from 472992-471337, reverse complement, Uncharacterized ORF [yeastflysequest.fasta]
  • Ykr017cp [Saccharomyces cerevisiae]gi|486435|emb|CAA82089.1| unnamed protein product [Saccharomyces cerevisiae]gi|539235|pir||S38086 hypothetical protein YKR017c - yeast (Saccharomyces cerevisiae)gi|549769|sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa pro [nrdb_11152004_Chlamydomonas]
  • YKR017C SGDID:S000001725, Chr XI from 472992-471337, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a RING finger motif" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta]
  • unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • RING finger protein YKR017C [nr-271106-contam.fasta]
  • Putative protein of unknown function; contains a RING finger motif; Ykr017cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta]
  • [chemostatdb.fasta]
  • RING finger protein YKR017C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YKR017C PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta]
  • YKR017C SGDID:S000001725, Chr XI from 473349-471694, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a RING finger motif" [yeast-030211-contam.fasta]
  • HEL1 SGDID:S000001725, Chr XI from 473349-471694, Genome Release 64-2-1, reverse complement, Verified ORF, "RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU)" [20141208_orf_trans.fasta]
  • E3 ubiquitin-protein ligase HEL2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HEL1 PE=1 SV=1 [uniprot_sprot.fasta.20160308]
    • Organism: Saccharomyces cerevisiae
    Length: 551 amino acids

    Gene Ontology:
    Cellular Component: cellular_component [ND]
    Biological Process: biological_process [ND]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGTENDQF YSFDESDSSS IELYESHNTS EFTIHGLVFP KLISVTSQDS EFDINEDEDG  60
   61 VDTIYEGMLD APLTKNNKRI LCEGSVPNLS YECLTTKGIF ERMLQRVDHL QPIFAIPSAD 120
  121 ILILLQHYDW NEERLLEVWT EKMDELLVEL GLSTTANIKK DNDYNSHFRE VEFKNDFTCI 180
  181 ICCDKKDTET FALECGHEYC INCYRHYIKD KLHEGNIITC MDCSLALKNE DIDKVMGHPS 240
  241 SSKLMDSSIK SFVQKHNRNY KWCPFADCKS IVHLRDTSSL PEYTRLHYSP FVKCNSFHRF 300
  301 CFNCGFEVHS PADCKITTAW VKKARKESEI LNWVLSHTKE CPKCSVNIEK NGGCNHMVCS 360
  361 SCKYEFCWIC EGPWAPHGKN FFQCTMYKNN EDNKSKNPQD ANKTLKKYTF YYRLFNEHEV 420
  421 SAKLDWNLGQ TLGTKVHALQ ERIGISWIDG QFLSESLKVL NEGRTVLKWS FAVAYYSDAS 480
  481 HNLTKIFVDN QMLLANAVES LSELLQIKTP EVIMKRRPEF YNKAGYVENR TTALMECGRE 540
  541 LLCKGICKAA E

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ETP1 MOH1 NHA1 YKR017C

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #20 Asynchronous Prep1-TiO2 Phosphopeptide enrichment, PartB Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] deduced N/A No confident structure predictions are available.
    2 View Details [155..293] PSI-BLAST 2.045757 V(D)J recombination activating protein 1 (RAG1), dimerization domain
    3 View Details [294..386] deduced N/A No confident structure predictions are available.
    4 View Details [387..551] MSA 3.105962 View MSA. No confident structure predictions are available.
    5 View Details [392..551] MSA 7.15898 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • ubiquitin-protein ligase activity
    		•  5.65442784325159 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  5.55686022186257 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  4.59153177011595 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  3.07217714843839 bayes_pls_golite062009
  • binding
    		•  2.19426901055464 bayes_pls_golite062009
  • protein binding
    		•  1.62051249360163 bayes_pls_golite062009
  • small conjugating protein-specific protease activity
    		•  1.2126425713931 bayes_pls_golite062009
  • ubiquitin-specific protease activity
    		•  1.03469202541773 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.708499177773075 bayes_pls_golite062009
  • ligase activity
    		•  0.63517530468004 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.553991532499653 bayes_pls_golite062009
  • cysteine-type peptidase activity
    		•  0.50197530717959 bayes_pls_golite062009
  • ubiquitin thiolesterase activity
    		•  0.265769062717221 bayes_pls_golite062009
  • DNA binding
    		•  0.227671243150662 bayes_pls_golite062009
  • hydrolase activity
    		•  0.156835837705934 bayes_pls_golite062009
  • catalytic activity
    		•  0.14112008370434 bayes_pls_golite062009
  • peptidase activity
    		•  0.121357659741468 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle