YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: SLD2

General Information:
Name(s) found: SLD2 / YKL108W [SGD]
Description(s) found:
Found 26 descriptions.
SHOW ALL
  • Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 453 amino acids

    Gene Ontology:
    Cellular Component: replication fork [IGILink to PubMed article][IPILink to PubMed article]
    Biological Process: DNA strand elongation involved in DNA replication [IGILink to PubMed article][IPILink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYSFELDKLK IELKTWEHDF IDKNKREPTR DDIKSLRTVR QMYKQYSTLK KKQSLQRQKV  60
   61 DTQESVELPA HKKDHDEVVE IGPTPQVYGK AISIFDMNLS PIKPIYMTFT NNIDVNNDNS 120
  121 KTISNESSPR KTILLKSSPA DRTLVAEPIS SVKRQLNFQM LNASSTRTPT SSPCKNRNGK 180
  181 LVEIKKCSPT INPPLESGKP SGYYGPNSPL KLDEENIHLN ISLNSSTKRR LQIAYPSLQK 240
  241 TPSKDQADIS TSFSPSPLIR RPLTKSLIEL AREHTEIVKE FGVLQEEDIE EEEEGEEGEN 300
  301 GYDEKNHEDD FGLEDELIRP KVVKDIFQED DDNDDSQARE DTFIRKRPKR RKVIRRLRDN 360
  361 DPETETAGFE RDVHKELVKL KRRKVAEFLG STSQISDTEF EHDPEASSGV VSSEQKPTAK 420
  421 RKGRKKYNLV SNNFRRLKLP KKNRFSNGRW GRR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) ALD6 CCT8 CYS4 ERG11 ERR3 HSP150 SLD2 TUB2 WAR1
    View Details Ho Y, et al. (2002) ADH2 ADH4 CKA1 COP1 DSS1 GAL7 IPP1 MAM33 MDH1 MGE1 PTC7 SLD2 SRP1 TAL1 TRL1
    View Details Qiu et al. (2008) DPB3 POL30 POL31 SLD2

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data SLD2 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..315] ab initio 8.97 No description for 1ldvA was found.
    2 View Details [316..453] deduced N/A No confident structure predictions are available.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle