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Protein Overview: RSF2

General Information:
Name(s) found: RSF2 / YJR127C [SGD]
Description(s) found:
Found 27 descriptions.
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  • Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 1380 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    Biological Process: regulation of transcription [IMPLink to PubMed article]
    Molecular Function: transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPFAFGRGA PALCILTAAA RINLDNFVPC CWALFRLSFF FPLDPAYIRN ENKETRTSWI  60
   61 SIEFFFFVKH CLSQHTFFSK TLAPKRNFRA KKLKDIGDTR IDRADKDFLL VPEPSMFVNG 120
  121 NQSNFAKPAG QGILPIPKKS RIIKTDKPRP FLCPTCTRGF VRQEHLKRHQ HSHTREKPYL 180
  181 CIFCGRCFAR RDLVLRHQQK LHAALVGTGD PRRMTPAPNS TSSFASKRRH SVAADDPTDL 240
  241 HIIKIAGNKE TILPTPKNLA GKTSEELKEA VVALAKSNNV ELPVSAPVMN DKREKTPPSK 300
  301 AGSLGFREFK FSTKGVPVHS ASSDAVIDRA NTPSSMHKTK RHASFSASSA MTYMSSSNSP 360
  361 HHSITNFELV EDAPHQVGFS TPQMTAKQLM ESVSELDLPP LTLDEPPQAI KFNLNLFNND 420
  421 PSGQQQQQQQ QQQNSTSSTI VNSNNGSTVA TPGVYLLSSG PSLTDLLTMN SAHAGAGGYM 480
  481 SSHHSPFDLG CFSHDKPTVS EFNLPSSFPN TIPSNSTTAS NSYSNLANQT YRQMSNEQPL 540
  541 MSLSPKNPPT TVSDSSSTIN FNPGTNNLLE PSMEPNDKDS NIDPAAIDDK WLSEFINNSD 600
  601 PKSTFKINFN HFNDIGFIYS PPSSRSSIPN KSPPNHSATS LNHEKASLSP RLNLSLNGST 660
  661 DLPSTPQNQL KEPSYSDPIS HSSHKRRRDS VMMDYDLSNF FSSRQLDISK VLNGTEQNNS 720
  721 HVNDDVLTLS FPGETDSNAT QKQLPVLTPS DLLSPFSVPS VSQVLFTNEL RSMMLADNNI 780
  781 DSGAFPTTSQ LNDYVTYYKE EFHPFFSFIH LPSIIPNMDS YPLLLSISMV GALYGFHSTH 840
  841 AKVLANAAST QIRKSLKVSE KNPETTELWV IQTLVLLTFY CIFNKNTAVI KGMHGQLTTI 900
  901 IRLLKASRLN LPLESLCQPP IESDHIMEYE NSPHMFSKIR EQYNAPNQMN KNYQYFVLAQ 960
  961 SRIRTCHAVL LISNLFSSLV GADCCFHSVD LKCGVPCYKE ELYQCRNSDE WSDLLCQYKI1020
 1021 TLDSKFSLIE LSNGNEAYEN CLRFLSTGDS FFYGNARVSL STCLSLLISI HEKILIERNN1080
 1081 ARISNNNTNS NNIELDDIEW KMTSRQRIDT MLKYWENLYL KNGGILTPTE NSMSTINANP1140
 1141 AMRLIIPVYL FAKMRRCLDL AHVIEKIWLK DWSNMNKALE EVCYDMGSLR EATEYALNMV1200
 1201 DAWTSFFTYI KQGKRRIFNT PVFATTCMFT AVLVISEYMK CVEDWARGYN ANNPNSALLD1260
 1261 FSDRVLWLKA ERILRRLQMN LIPKECDVLK SYTDFLRWQD KDALDLSALN EEQAQRAMDP1320
 1321 NTDINETIQL IVAASLSSKC LYLGVQILGD APIWPIILSF AHGLQSRAIY SVTKKRNTRI1380
 1381

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Ho Y, et al. (2002) ELP2 ELP3 IKI3 NIS1 RSF2

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #19 Asynchronous Prep1-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #29 Asynchronous Prep5-TiO2 Flowthrough Keck JM, et al. (2011)
    View Run MLP2 #19b Asynchronous Prep1-new search criteria Keck JM, et al. (2011)
    View Run MLP2 #19a Asynchronous Prep1-new search criteria Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen PRP16 RSF2 2 Unpublished Fields Lab Data
    View Screen VPS17 RSF2 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RSF2 Huh WK, et al. (2003)
    View Data RSF2 and NOP56 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] PSI-BLAST 61.144602 Five-finger GLI1
    2 View Details [93..202] deduced N/A No confident structure predictions are available.
    3 View Details [203..247] PSI-BLAST 2.39794 Tramtrack protein (two zinc-finger peptide)
    4 View Details [248..323] MSA 4.824996 View MSA. No confident structure predictions are available.
    5 View Details [324..562] deduced N/A No confident structure predictions are available.
    6 View Details [563..1380] MSA 1.049001 View MSA. No confident structure predictions are available.
    7 View Details [1218..1380] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transcription regulator activity
    		•  4.70988788192472 bayes_pls_golite062009
  • DNA binding
    		•  4.56219307357342 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.28215395396923 bayes_pls_golite062009
  • transcription factor activity
    		•  3.50954949535763 bayes_pls_golite062009
  • binding
    		•  3.10743787485868 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.31369346002275 bayes_pls_golite062009
  • transcription activator activity
    		•  2.19952417915035 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.64349785387632 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  1.42975942698743 bayes_pls_golite062009
  • transcription factor binding
    		•  1.39608963544799 bayes_pls_golite062009
  • chromatin binding
    		•  1.37132088004982 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.0497955246512 bayes_pls_golite062009
  • protein binding
    		•  1.00484935878505 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.77874411480713 bayes_pls_golite062009
  • catalytic activity
    		•  0.245893663605433 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.10558148421807 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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