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Protein Overview: ECM25

General Information:
Name(s) found: ECM25 / YJL201W [SGD]
Description(s) found:
Found 24 descriptions.
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  • Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 599 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: filamentous growth [IMPLink to PubMed article]
    response to drug [IMPLink to PubMed article]
    cellular cell wall organization [IMPLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDINVNNIF FRSYSVDPNS GHAIYVFDST YLPASDEIGD KQVYDLLINA LMDRLVMKLP  60
   61 QAPYSLVIFS SGFSQRKISW VYGIKMFAKL PKETKFYLQK IFIVHESFFV RSVYQVISNA 120
  121 MNFNFLDSKD SQHDFPSLVH VLDLTSLSEL IDITRLRISL NVYLYDYQIR EHINVPEEYY 180
  181 NRLTPLAIRQ YRQLVFDKIF KKLQNDALLC ELIFQKPGNY KKVNIFLDII KRNNYIDLSQ 240
  241 WDIYSLASVW LNYFIKNKAK PLIPIELIPL PIVDDLKFTS ETFRKIIKFN QYQDLFMVII 300
  301 PFFNRIIAHG ESTKHDSRTL SKALTPALCK EKLSMMTNDR LAIGSRYIKN LLDFFPEIAK 360
  361 EISSPPSSVS SSSTIPVLPK PRKSSPTRYS ELGCLTLPRS RSPSPQRSVT SPTYTPVALQ 420
  421 NTPVLKPKSS SRNVSSPSFN AKPPLPIKAV TRPQLSLTSN SNTDLALASS STDTLSSPTK 480
  481 TPSADSLPLS NSSTDLTISD NIKEMVKDEP AKDKNSVETD IFVQQFESLT LVQNAKIKKF 540
  541 DKELQEKKKK NETTSKTADK FSQKGYSDIK ASNKVSRLAA LYEERLQGLQ VMNEMKQRW

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Gavin AC, et al. (2006) BZZ1 ECM25
    View Details Gavin AC, et al. (2002) BSP1 BZZ1 CHC1 ECM25 END3 INP52 LAS17 LSB3 RAD51 SLA1 SLA2 STM1 SYP1 TFP1 VRP1 YPT7 YSC84

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run PAN1 No Comments Toshima J, et al (2006)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen SLA1 ECM25 2 Unpublished Fields Lab Data

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data ECM25 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] MSA 4.028988 View MSA. No confident structure predictions are available.
    2 View Details [134..259] PSI-BLAST 43.522879 p50 RhoGAP domain
    3 View Details [260..364] PSI-BLAST 43.522879 p50 RhoGAP domain
    4 View Details [365..599] ORFEUS 14.42 Sec24

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.66936642189191 bayes_pls_golite062009
  • protein binding
    		•  0.602166427548399 bayes_pls_golite062009
    2
    Term Confidence Notes
  • nucleoside-triphosphatase regulator activity
    		•  2.43743506044906 bayes_pls_golite062009
  • GTPase regulator activity
    		•  2.41587723604351 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.31135086896701 bayes_pls_golite062009
  • GTPase activator activity
    		•  2.15573543632895 bayes_pls_golite062009
  • enzyme activator activity
    		•  2.13776259591853 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  1.99641315605345 bayes_pls_golite062009
  • Ras GTPase activator activity
    		•  1.8516163173153 bayes_pls_golite062009
  • Rho GTPase activator activity
    		•  1.661551260799 bayes_pls_golite062009
  • binding
    		•  1.47992835441063 bayes_pls_golite062009
  • protein binding
    		•  1.42235437592444 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle