| Protein: | ECM25 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 599 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ECM25.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..599] | [1..599] |
|
|
5.0E-96 | [14..398] | [61..461] |
|
|
7.0E-95 | [14..360] | [75..432] |
|
|
1.0E-94 | [14..364] | [98..459] |
|
|
2.0E-74 | [11..359] | [100..464] |
|
Region A: Residues: [1-133] |
1 11 21 31 41 51
| | | | | |
1 MIDINVNNIF FRSYSVDPNS GHAIYVFDST YLPASDEIGD KQVYDLLINA LMDRLVMKLP 60
61 QAPYSLVIFS SGFSQRKISW VYGIKMFAKL PKETKFYLQK IFIVHESFFV RSVYQVISNA 120
121 MNFNFLDSKD SQH
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| binding | 1.66936642189191 | bayes_pls_golite062009 |
| protein binding | 0.602166427548399 | bayes_pls_golite062009 |
|
Region A: Residues: [134-259] |
1 11 21 31 41 51
| | | | | |
1 DFPSLVHVLD LTSLSELIDI TRLRISLNVY LYDYQIREHI NVPEEYYNRL TPLAIRQYRQ 60
61 LVFDKIFKKL QNDALLCELI FQKPGNYKKV NIFLDIIKRN NYIDLSQWDI YSLASVWLNY 120
121 FIKNKA
|
| Detection Method: | |
| Confidence: | 43.522879 |
| Match: | 1rgp__ |
| Description: | p50 RhoGAP domain |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| nucleoside-triphosphatase regulator activity | 2.43743506044906 | bayes_pls_golite062009 |
| GTPase regulator activity | 2.41587723604351 | bayes_pls_golite062009 |
| enzyme regulator activity | 2.31135086896701 | bayes_pls_golite062009 |
| GTPase activator activity | 2.15573543632895 | bayes_pls_golite062009 |
| enzyme activator activity | 2.13776259591853 | bayes_pls_golite062009 |
| small GTPase regulator activity | 1.99641315605345 | bayes_pls_golite062009 |
| Ras GTPase activator activity | 1.8516163173153 | bayes_pls_golite062009 |
| Rho GTPase activator activity | 1.661551260799 | bayes_pls_golite062009 |
| binding | 1.47992835441063 | bayes_pls_golite062009 |
| protein binding | 1.42235437592444 | bayes_pls_golite062009 |
|
Region A: Residues: [260-364] |
1 11 21 31 41 51
| | | | | |
1 KPLIPIELIP LPIVDDLKFT SETFRKIIKF NQYQDLFMVI IPFFNRIIAH GESTKHDSRT 60
61 LSKALTPALC KEKLSMMTND RLAIGSRYIK NLLDFFPEIA KEISS
|
| Detection Method: | |
| Confidence: | 43.522879 |
| Match: | 1rgp__ |
| Description: | p50 RhoGAP domain |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [365-599] |
1 11 21 31 41 51
| | | | | |
1 PPSSVSSSST IPVLPKPRKS SPTRYSELGC LTLPRSRSPS PQRSVTSPTY TPVALQNTPV 60
61 LKPKSSSRNV SSPSFNAKPP LPIKAVTRPQ LSLTSNSNTD LALASSSTDT LSSPTKTPSA 120
121 DSLPLSNSST DLTISDNIKE MVKDEPAKDK NSVETDIFVQ QFESLTLVQN AKIKKFDKEL 180
181 QEKKKKNETT SKTADKFSQK GYSDIKASNK VSRLAALYEE RLQGLQVMNE MKQRW
|
| Detection Method: | |
| Confidence: | 14.42 |
| Match: | 1m2vB |
| Description: | Sec24 |
Matching Structure (courtesy of the PDB): |
|
