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Protein Overview: RPE1

General Information:
Name(s) found: RPE1 / YJL121C [SGD]
Description(s) found:
Found 31 descriptions.
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  • D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 238 amino acids

    Gene Ontology:
    Cellular Component: cytosol [TASLink to PubMed article]
    Biological Process: pentose-phosphate shunt [IMPLink to PubMed article]
    Molecular Function: ribulose-phosphate 3-epimerase activity [IDALink to PubMed article][IMPLink to PubMed article][ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKPIIAPSI LASDFANLGC ECHKVINAGA DWLHIDVMDG HFVPNITLGQ PIVTSLRRSV  60
   61 PRPGDASNTE KKPTAFFDCH MMVENPEKWV DDFAKCGADQ FTFHYEATQD PLHLVKLIKS 120
  121 KGIKAACAIK PGTSVDVLFE LAPHLDMALV MTVEPGFGGQ KFMEDMMPKV ETLRAKFPHL 180
  181 NIQVDGGLGK ETIPKAAKAG ANVIVAGTSV FTAADPHDVI SFMKEEVSKE LRSRDLLD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run RPA135 his-HA tag on RPA135 Schneider, DA, et al. (2006)
    View Run MLP2 #03 Alpha Factor Prep1-TiO2 Flowthrough Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data RPE1 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] PSI-BLAST 421.94696 D-ribulose-5-phosphate 3-epimerase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribulose-phosphate 3-epimerase activity
    		•  3.28372503209224 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • intramolecular oxidoreductase activity
    		•  1.86158562896415 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting aldoses and ketoses
    		•  1.36492964250879 bayes_pls_golite062009
  • isomerase activity
    		•  0.935800409577999 bayes_pls_golite062009
  • racemase and epimerase activity, acting on carbohydrates and derivatives
    		•  0.764608070506109 bayes_pls_golite062009
  • orotidine-5'-phosphate decarboxylase activity
    		•  0.758594564254247 bayes_pls_golite062009
  • binding
    		•  0.595171555788202 bayes_pls_golite062009
  • racemase and epimerase activity
    		•  0.288948763149344 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  0.1100847613283 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.62

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle