Protein Overview: GUT2

General Information:
Name(s) found:	GUT2 / YIL155C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|729614\|sp\|P32191.2\|GPDM_YEAST RecName: Full=Glycerol-3-phosphate dehydrogenase, mitochondrial; Short=GPDH-M; Short=GPD-M; Flags: Precursor [NCBI NR] gi\|6322036\|ref\|NP_012111.1\| Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner; Gut2p [Saccharomyces c [NCBI NR] pir\|\|S48379 glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) precursor, mitochondrial - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|557768\|emb\|CAA86123.1\| glycerol-3-phosphate dehydrogenase [Saccharomyces cerevisiae] [NCBI NR] Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae GN=GUT2 PE=1 SV=2 [Swiss-Prot] GUT2 Glycerol-3-phosphate dehydrogenase, mitochondrial [mips] Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner [SGD] GUT2, Chr IX from 51759-53708, reverse complement [yeast_orfs2] Chr IX from 51759-53708, reverse complement [yeastorf3.fasta] Chr IX from 53708-51759, reverse complement [yeastorf5.fasta] (P32191) Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (EC 1.1.99.5) (GPD-M) (GPDH-M) [4932.FASTACCERV.txt] GUT2 SGDID:S0001417, Chr IX from 53708-51759, reverse complement, Verified ORF [yeastflysequest.fasta] Gut2p [Saccharomyces cerevisiae]gi\|557768\|emb\|CAA86123.1\| glycerol-3-phosphate dehydrogenase [Saccharomyces cerevisiae]gi\|630008\|pir\|\|S48379 glycerol-3-phosphate dehydrogenase (EC 1.1.99.5) precursor, mitochondrial - yeast (Saccharomyces cerevisiae)gi\| [nrdb_11152004_Chlamydomonas] GUT2 SGDID:S000001417, Chr IX from 53708-51759, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2 [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] glycerol-3-phosphate dehydrogenase [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner; Gut2p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Glycerol-3-phosphate dehydrogenase, mitochondrial precursor (GPD-M) (GPDH-M) [nr-271106-contam.fasta] GUT2 SGDID:S000001417, Chr IX from 53708-51759, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GUT2 PE=1 SV=2 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] GUT2 SGDID:S000001417, Chr IX from 53708-51759, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" [yeast-030211-contam.fasta] GUT2 SGDID:S000001417, Chr IX from 53708-51759, Genome Release 64-2-1, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" [20141208_orf_trans.fasta] TR3963\|c0_g1_i1\|g.2814 ORF TR3963\|c0_g1_i1\|g.2814 TR3963\|c0_g1_i1\|m.2814 type:complete len:650 (+) TR3963\|c0_g1_i1:1576-3525(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR8797\|c0_g1_i1\|g.6232 ORF TR8797\|c0_g1_i1\|g.6232 TR8797\|c0_g1_i1\|m.6232 type:complete len:650 (+) TR8797\|c0_g1_i1:1585-3534(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YIL155C SGDID:S000001417, Chr IX from 53708-51759, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] asmbl_8835\|g.6537 ORF asmbl_8835\|g.6537 asmbl_8835\|m.6537 type:complete len:650 (+) asmbl_8835:1612-3561(+) [Y12_Trinity_v2_2_0_PASA_6May2016-contam.fasta] ID=asmbl_8872\|g.5372 ORF ID=asmbl_8872\|g.5372 ID=asmbl_8872\|m.5372 type:complete len:650 (+) ID=asmbl_8872:1585-3534(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_8841\|g.5483 ORF ID=asmbl_8841\|g.5483 ID=asmbl_8841\|m.5483 type:complete len:650 (+) ID=asmbl_8841:1612-3561(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	649 amino acids
Gene Ontology:
Cellular Component:	integral to mitochondrial outer membrane [IDA] mitochondrion [IDA ][IMP][ISS]
Biological Process:	carbohydrate metabolic process [IMP] NADH oxidation [IDA]
Molecular Function:	glycerol-3-phosphate dehydrogenase activity [IDA][IMP][ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSVTRRRAA GAAAAMATAT GTLYWMTSQG DRPLVHNDPS YMVQFPTAAP PQVSRRDLLD  60
   61 RLAKTHQFDV LIIGGGATGT GCALDAATRG LNVALVEKGD FASGTSSKST KMIHGGVRYL 120
  121 EKAFWEFSKA QLDLVIEALN ERKHLINTAP HLCTVLPILI PIYSTWQVPY IYMGCKFYDF 180
  181 FAGSQNLKKS YLLSKSATVE KAPMLTTDNL KASLVYHDGS FNDSRLNATL AITAVENGAT 240
  241 VLNYVEVQKL IKDPTSGKVI GAEARDVETN ELVRINAKCV VNATGPYSDA ILQMDRNPSG 300
  301 LPDSPLNDNS KIKSTFNQIA VMDPKMVIPS IGVHIVLPSF YCPKDMGLLD VRTSDGRVMF 360
  361 FLPWQGKVLA GTTDIPLKQV PENPMPTEAD IQDILKELQH YIEFPVKRED VLSAWAGVRP 420
  421 LVRDPRTIPA DGKKGSATQG VVRSHFLFTS DNGLITIAGG KWTTYRQMAE ETVDKVVEVG 480
  481 GFHNLKPCHT RDIKLAGAEE WTQNYVALLA QNYHLSSKMS NYLVQNYGTR SSIICEFFKE 540
  541 SMENKLPLSL ADKENNVIYS SEENNLVNFD TFRYPFTIGE LKYSMQYEYC RTPLDFLLRR 600
  601 TRFAFLDAKE ALNAVHATVK VMGDEFNWSE KKRQWELEKT VNFIKTFGV

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		AIM45 ALD4 CIR1 CIR2 CIT1 CYB2 DLD1 FUM1 GUT2 MDH1 NDE1 NDE2 NDI1 SDH1
View Details	Qiu et al. (2008)		BNA4 CIR2 COQ6 DLD1 GUT2 HFD1 NDE1 NDI1 SDH1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)
View Run	ZDS1	Sample 3 - cpn + atp, from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	GUT2	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..497]	PSI-BLAST	40.69897	Sarcosine oxidase
2	View Details	[498..570]	deduced	N/A	No confident structure predictions are available.
3	View Details	[571..649]	MSA	3.073982	View MSA. Confident ab initio structure predictions are available.

Protein Overview: GUT2

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: