YRC Public Data Repository - Protein Structure Prediction

Protein:	GUT2
Organism:	Saccharomyces cerevisiae
Length:	649 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GUT2.

Description	E-value	Query Range	Subject Range
gi\|51013185 - gi\|51013185\|gb\|AAT92886.1\| YIL155C [Saccharomyces cerevisiae]	539.0	[0..24]	[649..24]
gi\|62088378 - gi\|62088378\|dbj\|BAD92636.1\| glycerol-3-phosphate dehydrogenase 2 (mitochondrial) variant [Homo sapie...	515.0	[0..7]	[644..12]
h0014824 - null GPD2 - glycerol-3-phosphate dehydrogenase 2 (mitochondrial) gi\|114581287, gi... - gi\|114581291\|ref\|XP_001143123.1\| PREDICTED: glycerol-3-phosphate dehydrogenase 2 (mitochondrial) iso...	514.0	[0..7]	[644..11]
gi\|76660061 - gi\|76660061\|ref\|XP_878104.1\| PREDICTED: similar to Glycerol-3-phosphate dehydrogenase, mitochondrial...	507.0	[0..7]	[644..11]
gi\|109099744, gi... - gi\|109099750\|ref\|XP_001087302.1\| PREDICTED: glycerol-3-phosphate dehydrogenase 2 (mitochondrial) iso...	501.0	[0..7]	[644..11]
GPDM_MACFA - Glycerol-3-phosphate dehydrogenase, mitochondrial OS=Macaca fascicularis GN=GPD2 PE=2 SV=1	500.0	[0..7]	[644..11]

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Predicted Domain #1

Region A:
Residues: [1-497]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFSVTRRRAA GAAAAMATAT GTLYWMTSQG DRPLVHNDPS YMVQFPTAAP PQVSRRDLLD  60
   61 RLAKTHQFDV LIIGGGATGT GCALDAATRG LNVALVEKGD FASGTSSKST KMIHGGVRYL 120
  121 EKAFWEFSKA QLDLVIEALN ERKHLINTAP HLCTVLPILI PIYSTWQVPY IYMGCKFYDF 180
  181 FAGSQNLKKS YLLSKSATVE KAPMLTTDNL KASLVYHDGS FNDSRLNATL AITAVENGAT 240
  241 VLNYVEVQKL IKDPTSGKVI GAEARDVETN ELVRINAKCV VNATGPYSDA ILQMDRNPSG 300
  301 LPDSPLNDNS KIKSTFNQIA VMDPKMVIPS IGVHIVLPSF YCPKDMGLLD VRTSDGRVMF 360
  361 FLPWQGKVLA GTTDIPLKQV PENPMPTEAD IQDILKELQH YIEFPVKRED VLSAWAGVRP 420
  421 LVRDPRTIPA DGKKGSATQG VVRSHFLFTS DNGLITIAGG KWTTYRQMAE ETVDKVVEVG 480
  481 GFHNLKPCHT RDIKLAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	40.69897
Match:	1el5A
Description:	Sarcosine oxidase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [498-570]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AEEWTQNYVA LLAQNYHLSS KMSNYLVQNY GTRSSIICEF FKESMENKLP LSLADKENNV  60
   61 IYSSEENNLV NFD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [571-649]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TFRYPFTIGE LKYSMQYEYC RTPLDFLLRR TRFAFLDAKE ALNAVHATVK VMGDEFNWSE  60
   61 KKRQWELEKT VNFIKTFGV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.935	N/A	N/A	a.52.1	Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits