Protein Overview: MSC7

General Information:
Name(s) found:	MSC7 / YHR039C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|731651\|sp\|P38694.1\|YHJ9_YEAST RecName: Full=Putative aldehyde dehydrogenase-like protein YHR039C [NCBI NR] gi\|6321828\|ref\|NP_011904.1\| Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids; Msc7p [Saccharom [NCBI NR] pir\|\|S46746 hypothetical protein YHR039c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|488180\|gb\|AAB68915.1\| Yhr039cp [Saccharomyces cerevisiae] [NCBI NR] Putative aldehyde dehydrogenase-like protein YHR039C OS=Saccharomyces cerevisiae GN=YHR039C PE=1 SV=1 [Swiss-Prot] Putative aldehyde dehydrogenase-like protein YHR039C OS=Saccharomyces cerevisiae GN=MSC7 PE=1 SV=1 [Swiss-Prot] MSC7 Endoplasmic reticulum, role in directing meiotic recombination events to homologous chromatids [mips] Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids [SGD] MSC7, Chr VIII from 184866-186800, reverse complement [yeast_orfs2] Chr VIII from 184866-186800, reverse complement [yeastorf3.fasta] Chr VIII from 186800-184866, reverse complement [yeastorf5.fasta] (P38694) Hypothetical aldehyde-dehydrogenase like protein in FIL1-VMA10 intergenic region (EC 1.2.1.-) [4932.FASTACCERV.txt] MSC7 SGDID:S0001081, Chr VIII from 186801-184867, reverse complement, Verified ORF [yeastflysequest.fasta] Msc7p [Saccharomyces cerevisiae]gi\|731651\|sp\|P38694\|YHJ9_YEAST Hypothetical aldehyde-dehydrogenase like protein in FIL1-VMA10 intergenic regiongi\|626608\|pir\|\|S46746 hypothetical protein YHR039c - yeast (Saccharomyces cerevisiae)gi\|488180\|gb\|AAB68915.1\| [nrdb_11152004_Chlamydomonas] MSC7 SGDID:S000001081, Chr VIII from 186802-184868, reverse complement, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic reco [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] Putative aldehyde dehydrogenase-like protein YHR039C [nr-271106-contam.fasta] Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids; Msc7p [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Yhr039cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] MSC7 SGDID:S000001081, Chr VIII from 186802-184868, reverse complement, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" [yeast-bovrabprots.fasta] [chemostatdb.fasta] Putative aldehyde dehydrogenase-like protein YHR039C OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MSC7 PE=1 SV=1 [UniProt_S_cerevisiae_20120516_05-16-2012_reversed.fasta] MSC7 SGDID:S000001081, Chr VIII from 186809-184875, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" [yeast-030211-contam.fasta] MSC7 SGDID:S000001081, Chr VIII from 186809-184875, Genome Release 64-2-1, reverse complement, Verified ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" [20141208_orf_trans.fasta] TR4952\|c0_g1_i1\|g.3480 ORF TR4952\|c0_g1_i1\|g.3480 TR4952\|c0_g1_i1\|m.3480 type:complete len:645 (+) TR4952\|c0_g1_i1:112-2046(+) [Y12_S_cerevisiae-Sep2015-contam.fasta] TR1993\|c0_g1_i1\|g.1386 ORF TR1993\|c0_g1_i1\|g.1386 TR1993\|c0_g1_i1\|m.1386 type:complete len:645 (+) TR1993\|c0_g1_i1:150-2084(+) [DBVPG6044_S_cerevisiae-Sep2015-contam.fasta] YHR039C SGDID:S000001081, Chr VIII from 186809-184875, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta] ID=asmbl_7940\|g.4969 ORF ID=asmbl_7940\|g.4969 ID=asmbl_7940\|m.4969 type:complete len:645 (+) ID=asmbl_7940:149-2083(+) [DBVPG6044_quiverGenomes_Trinity_v2_2_0_PASA_2June2016-contam.fasta] ID=asmbl_7992\|g.4994 ORF ID=asmbl_7992\|g.4994 ID=asmbl_7992\|m.4994 type:complete len:645 (+) ID=asmbl_7992:149-2083(+) [Y12_quiver_Trinity_v2_2_0_PASA_2June2016-contam.fasta]
Organism:	Saccharomyces cerevisiae
Length:	644 amino acids
Gene Ontology:
Cellular Component:	endoplasmic reticulum [IDA]
Biological Process:	reciprocal meiotic recombination [IMP]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVYLNSDM INHLNSTVQA YFNLWLEKQN AIMRSQPQII QDNQKLIGIT TLVASIFTLY  60
   61 VLVKIISTPA KCSSSYKPVK FSLPAPEAAQ NNWKGKRSVS TNIWNPEEPN FIQCHCPATG 120
  121 QYLGSFPSKT EADIDEMVSK AGKAQSTWGN SDFSRRLRVL ASLHDYILNN QDLIARVACR 180
  181 DSGKTMLDAS MGEILVTLEK IQWTIKHGQR ALQPSRRPGP TNFFMKWYKG AEIRYEPLGV 240
  241 ISSIVSWNYP FHNLLGPIIA ALFTGNAIVV KCSEQVVWSS EFFVELIRKC LEACDEDPDL 300
  301 VQLCYCLPPT ENDDSANYFT SHPGFKHITF IGSQPVAHYI LKCAAKSLTP VVVELGGKDA 360
  361 FIVLDSAKNL DALSSIIMRG TFQSSGQNCI GIERVIVSKE NYDDLVKILN DRMTANPLRQ 420
  421 GSDIDHLENV DMGAMISDNR FDELEALVKD AVAKGARLLQ GGSRFKHPKY PQGHYFQPTL 480
  481 LVDVTPEMKI AQNEVFGPIL VMMKAKNTDH CVQLANSAPF GLGGSVFGAD IKECNYVANS 540
  541 LQTGNVAIND FATFYVCQLP FGGINGSGYG KFGGEEGLLG LCNAKSVCFD TLPFVSTQIP 600
  601 KPLDYPIRNN AKAWNFVKSF IVGAYTNSTW QRIKSLFSLA KEAS

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	Krogan NJ, et al. (2006)		ALG5 BRE5 CSN12 CUP2 DBP7 LUG1 MET10 MSC7 MSE1 NOP53 NPY1 PBP4 RPF2 RRS1 SAS5 UME6 YGR126W YHR127W YPR045C YRA1

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	RPA135	No Comments	Schneider, DA, et al. (2006)
View Run	ZDS1	Sample 2- cpn2 from june 2005	McCusker D, et al (2007)

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

	PROTEIN(S)	PUBLICATION
View Data	MSC7	Huh WK, et al. (2003)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..67]	deduced	N/A	No confident structure predictions are available.
2	View Details	[68..355] [554..644]	PSI-BLAST	1476.9897	Aldehyde reductase (dehydrogenase), ALDH
3	View Details	[356..553]	PSI-BLAST	1476.9897	Aldehyde reductase (dehydrogenase), ALDH

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.57

Protein Overview: MSC7

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: