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Protein Overview: HSP12

General Information:
Name(s) found: HSP12 / YFL014W [SGD]
Description(s) found:
Found 36 descriptions.
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  • Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 109 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    plasma membrane [IDALink to PubMed article]
    Biological Process: response to oxidative stress [TASLink to PubMed article]
    response to heat [TASLink to PubMed article]
    response to desiccation [IDALink to PubMed article][IEPLink to PubMed article]
    cell adhesion [IDALink to PubMed article]
    hyperosmotic response [TASLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDAGRKGFG EKASEALKPD SQKSYAEQGK EYITDKADKV AGKVQPEDNK GVFQGVHDSA  60
   61 EKGKDNAEGQ GESLADQARD YMGAAKSKLN DAVEYVSGRV HGEEDPTKK

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Krogan NJ, et al. (2006) DNA2 HSP12 PRO1 RFA1 RFA2 RFA3
    View Details Ho Y, et al. (2002) CPR1 HSP12

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

      BAIT PREY HITS PUBLICATION
    View Screen HSP12 UMP1 1 Unpublished Fields Lab Data
    View Screen HSP12 NFS1 1 Unpublished Fields Lab Data
    View Screen HSP12 RRT12 1 Unpublished Fields Lab Data
    View Screen HSP12 PCL10 1 Unpublished Fields Lab Data
    View Screen HSP12 YGL239C 1 Unpublished Fields Lab Data
    View Screen HSP12 YJR020W 1 Unpublished Fields Lab Data
    View Screen HSP12 NOP56 1 Unpublished Fields Lab Data
    View Screen HSP12 VPS36 1 Unpublished Fields Lab Data
    View Screen HSP12 TIF34 1 Unpublished Fields Lab Data
    View Screen HSP12 RTG1 1 Unpublished Fields Lab Data
    View Screen HSP12 YPR177C 1 Unpublished Fields Lab Data

    Microscopy / Localization Data

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      PROTEIN(S) PUBLICATION
    View Data HSP12 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..109] FFAS03 1.19 Human micelle-bound alpha-synuclein


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle