Protein Overview: DYN2

General Information:
Name(s) found:	DYN2 / YDR424C [SGD]
Description(s) found: Found 28 descriptions. SHOW ALL	Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex [SGD]
Organism:	Saccharomyces cerevisiae
Length:	92 amino acids
Gene Ontology:
Cellular Component:	cytoplasmic dynein complex [ISS] cytoplasmic microtubule [TAS]
Biological Process:	actin filament-based process [IGI] microtubule-based process [IGI]
Molecular Function:	microtubule motor activity [ISS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MSDENKSTPI VKASDITDKL KEDILTISKD ALDKYQLERD IAGTVKKQLD VKYGNTWHVI 60 61 VGKNFGSYVT HEKGHFVYFY IGPLAFLVFK TA

Protein Complex Data

	PUBLICATION	TOPOLOGY	COCOMPLEXED PROTEINS
View Details	(MIPS) Mewes HW, et al. (2004)		DYN1 DYN2 PAC11
View Details	Krogan NJ, et al. (2006)		DYN2 PAC11
View Details	Ho Y, et al. (2002)		DYN2 PAC11 PRX1
View Details	Qiu et al. (2008)		CIK1 DYN1 DYN2 DYN3 HSK3 KIP2 KIP3 PAC11

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	LOS1	DYN2	2	Unpublished Fields Lab Data
View Screen	PNO1	DYN2	1	Unpublished Fields Lab Data
View Screen	APC5	DYN2	1	Unpublished Fields Lab Data
View Screen	GPA1	DYN2	1	Unpublished Fields Lab Data

Microscopy / Localization Data

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	PROTEIN(S)	PUBLICATION
View Data	DYN2	Huh WK, et al. (2003)

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..92]	PSI-BLAST	258.035458	Dynein light chain 8 (DLC8)

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
microtubule motor activity	9.69298846835381	bayes_pls_golite062009
motor activity	5.85494716006373	bayes_pls_golite062009
dynein intermediate chain binding	4.30226487277718	bayes_pls_golite062009
nitric-oxide synthase regulator activity	3.06572632418145	bayes_pls_golite062009
dynein binding	2.90318309608701	bayes_pls_golite062009
cytoskeletal protein binding	2.8232927372914	bayes_pls_golite062009
binding	2.04793419379986	bayes_pls_golite062009
protein binding	1.75479345161448	bayes_pls_golite062009
nucleoside-triphosphatase activity	1.47503021587966	bayes_pls_golite062009
pyrophosphatase activity	1.40860884968216	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.39154744890125	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.38919307572739	bayes_pls_golite062009
ATPase activity, coupled	1.20571334292956	bayes_pls_golite062009
ATPase activity	0.96367371812709	bayes_pls_golite062009
catalytic activity	0.448769452796145	bayes_pls_golite062009
hydrolase activity	0.442050017414837	bayes_pls_golite062009
protein dimerization activity	0.257276734446829	bayes_pls_golite062009

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.91

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle