Protein Overview: ERT1

General Information:
Name(s) found:	ERT1 / YBR239C [SGD]
Description(s) found: SHOW ONLY BEST	gi\|6319716\|ref\|NP_009798.1\| Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR239C is not an essential gene; Ybr239cp [Saccharomyces cerevisiae] [NCBI NR] pir\|\|S46116 probable regulatory protein YBR239c - yeast (Saccharomyces cerevisiae) [NCBI NR] gi\|586354\|sp\|P38140.1\|YB89_YEAST RecName: Full=Uncharacterized transcriptional regulatory protein YBR239C [NCBI NR] gi\|536645\|emb\|CAA85202.1\| unnamed protein product [Saccharomyces cerevisiae] [NCBI NR] Uncharacterized transcriptional regulatory protein YBR239C OS=Saccharomyces cerevisiae GN=YBR239C PE=1 SV=1 [Swiss-Prot] Putative transcription factor [mips] Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition [SGD] YBR239C, Chr II from 698312-699901, reverse complement [yeast_orfs2] Chr II from 698312-699901, reverse complement [yeastorf3.fasta] Chr II from 698311-699900, reverse complement [yeastorf4.fasta] Chr II from 699898-698309, reverse complement [yeastorf5.fasta] (P38140) Putative 60.3 kDa transcriptional regulatory protein in PRP5-THI2 intergenic region [4932.FASTACCERV.txt] YBR239C SGDID:S0000443, Chr II from 699900-698311, reverse complement, Uncharacterized ORF [yeastflysequest.fasta] YBR239C SGDID:S0000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF [10112005cervSGD.fasta] Ybr239cp [Saccharomyces cerevisiae]gi\|536645\|emb\|CAA85202.1\| unnamed protein product [Saccharomyces cerevisiae]gi\|626836\|pir\|\|S46116 probable regulatory protein YBR239c - yeast (Saccharomyces cerevisiae)gi\|586354\|sp\|P38140\|YB89_YEAST Putative 60.3 kDa [nrdb_11152004_Chlamydomonas] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Hypothetical protein" [SGD_S-cerevisiae_na_12-16-2005_con_reversed.fasta] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR239C is not an essential gene" [yeast-contam.fasta] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; plays a role in restricting Ty1 tra [SGD_S-cerevisiae_na_08-19-2008_con_reversed.fasta] Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR239C is not an essential gene; Ybr239cp [Saccharomyces cerevisiae] [nr-271106-contam.fasta] Probable transcriptional regulatory protein YBR239C [nr-271106-contam.fasta] unnamed protein product [Saccharomyces cerevisiae] [nr-271106-contam.fasta] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm and nucleus; null mutation affects periodicity of transcriptional and metabo [SGD_S-cerevisiae_na_01-05-2010_reversed.fasta] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; plays a role in restricting Ty1 transposition" [yeast-bovrabprots.fasta] [chemostatdb.fasta] YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm and nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays a role in restricting Ty1 transposition" [SGDyeast.20101221.fasta] ERT1 SGDID:S000000443, Chr II from 699943-698354, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition" [yeast-030211-contam.fasta] ERT1 SGDID:S000000443, Chr II from 699943-698354, Genome Release 64-2-1, reverse complement, Verified ORF, "Transcriptional regulator; involved in regulation of gluconeogenesis and fermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition; member of the zinc cluster family of proteins, similar to Rds2p" [20141208_orf_trans.fasta] YBR239C SGDID:S000000443, Chr II from 699943-698354, Genome Release 64-1-1, reverse complement, Uncharacterized ORF, "Transcriptional regulator of nonfermentable carbon utilization; GFP-fusion protein localizes to cytoplasm, nucleus; null mutation affects periodicity of transcriptional and metabolic oscillation; plays role in restricting Ty1 transposition" [2016-01-SGD_Yeast_Contam_Riffle_20140507-Ska-Hec-110-tubulin.fasta]
Organism:	Saccharomyces cerevisiae
Length:	529 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA] cytoplasm [IDA]
Biological Process:	biological_process [ND]
Molecular Function:	molecular_function [ND]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCTPDENDYK TSTDPDTSAN TNHTLEKKKR KKRKNTNVAC VNCSRLHVSC EAKRPCLRCI  60
   61 SKGLTATCVD APRKKSKYLA GIPNRELPMN IQPDLPPRKI MIPIYNNSSN SSLNVNNMGE 120
  121 QQKFTSPQHI VHKAKFLSNA ADSEYSILSN IIYQDTLSNK IPIDILYSNT NSTSNSTIGN 180
  181 SSNNSPTGTN TSPEETEMEK IRQLYSEQRA NIPPHPYPSS NQNVYSILLG PNSAKIVASQ 240
  241 VNLFANHFPL VPVDSADNSL NFKRLLPRDP SEKSSQINWD SSINQYYLNS ETVTFPELAI 300
  301 PLKRRKNHLV SVSLESCSPD AANIKSNVEW EHSLRYSTPM EIYTSINAPF SHTPGFHHLL 360
  361 VYLKHRFNQQ DLVKMCRSIA EFRPIFIACS VTLTEEDMIF MEQCYQRTLL EYVKFIAQIG 420
  421 TPTCIWRRNG QISYVNEEFE ILCGWTREEL LNKMTFIVEI MDDESVRDYF KTLSKVAYRD 480
  481 FRGSEKMKVC RLLSPIKGKI IHCCCMWTLK RDVSGLPLMI LGNFMPILN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

The following runs contain data for this protein:

	BAIT	COMMENTS	PUBLICATION
View Run	ASF1	3912: TAP-tagged, strain background includes hpc2(delta)	Green EM, et al (2005)

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

	BAIT	PREY	HITS	PUBLICATION
View Screen	ERT1	PEX22	2	Unpublished Fields Lab Data
View Screen	ERT1	POP8	2	Unpublished Fields Lab Data
View Screen	ERT1	NEM1	2	Unpublished Fields Lab Data
View Screen	ERT1	RNP1	2	Unpublished Fields Lab Data
View Screen	ERT1	ISU2	2	Unpublished Fields Lab Data
View Screen	ERT1	RDS2	2	Unpublished Fields Lab Data
View Screen	YHR122W	ERT1	1	Hazbun TR, et al. (2003)
View Screen	PGA1	ERT1	1	Hazbun TR, et al. (2003)
View Screen	HRT1	ERT1	1	Unpublished Fields Lab Data

Microscopy / Localization Data

New Feature: Upload Your Own Microscopy Data

	PROTEIN(S)	PUBLICATION
View Data	ERT1	Huh WK, et al. (2003)

Protein Structure Data

[What does the above image mean?]
[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..171]	PSI-BLAST	9.0	Hap1 (Cyp1); HAP1
2	View Details	[172..353]	deduced	N/A	No confident structure predictions are available.
3	View Details	[354..529]	Pfam	13.346787	PAS fold No confident structure predictions are available.

Functions predicted (by domain):

Gene Ontology predictions

Term	Confidence	Notes
transcription regulator activity	3.46021754022299	bayes_pls_golite062009
nucleic acid binding	3.26455198324141	bayes_pls_golite062009
DNA binding	3.25588366587125	bayes_pls_golite062009
binding	2.32645838605286	bayes_pls_golite062009
transcription factor activity	2.20574348407066	bayes_pls_golite062009
RNA polymerase II transcription factor activity	1.54700248976411	bayes_pls_golite062009
sequence-specific DNA binding	1.34348800608209	bayes_pls_golite062009
specific RNA polymerase II transcription factor activity	1.28573362149629	bayes_pls_golite062009
transcription activator activity	0.335097584119319	bayes_pls_golite062009

No functions predicted.

Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2