YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FUS3

General Information:
Name(s) found: FUS3 / YBL016W [SGD]
Description(s) found:
Found 40 descriptions.
SHOW ALL
  • Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 353 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [IDALink to PubMed article]
    mitochondrion [IDALink to PubMed articleLink to PubMed article]
    mating projection tip [IDALink to PubMed article]
    Biological Process: cell cycle arrest [TASLink to PubMed article]
    invasive growth in response to glucose limitation [IMPLink to PubMed articleLink to PubMed articleLink to PubMed article]
    signal transduction during filamentous growth [IMPLink to PubMed article]
    protein amino acid phosphorylation [TASLink to PubMed article]
    pheromone-dependent signal transduction involved in conjugation with cellular fusion [IDALink to PubMed article]
    Molecular Function: MAP kinase activity [IDALink to PubMed article][TASLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRIVYNIS SDFQLKSLLG EGAYGVVCSA THKPTGEIVA IKKIEPFDKP LFALRTLREI  60
   61 KILKHFKHEN IITIFNIQRP DSFENFNEVY IIQELMQTDL HRVISTQMLS DDHIQYFIYQ 120
  121 TLRAVKVLHG SNVIHRDLKP SNLLINSNCD LKVCDFGLAR IIDESAADNS EPTGQQSGMT 180
  181 EYVATRWYRA PEVMLTSAKY SRAMDVWSCG CILAELFLRR PIFPGRDYRH QLLLIFGIIG 240
  241 TPHSDNDLRC IESPRAREYI KSLPMYPAAP LEKMFPRVNP KGIDLLQRML VFDPAKRITA 300
  301 KEALEHPYLQ TYHDPNDEPE GEPIPPSFFE FDHYKEALTT KDLKKLIWNE IFS

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details (MIPS) Mewes HW, et al. (2004) FUS3 KSS1 STE11 STE5 STE7
    View Details Krogan NJ, et al. (2006) FMS1 FUS3 RTT109 VPS75
    View Details Ho Y, et al. (2002) FUS3 HOG1 IDH2 MSG5 RCK1 ROD1 RPN8 SLT2 SNF1 TAL1
    View Details Qiu et al. (2008) CDC24 FUS3 KSS1 STE11 STE20 STE4 STE5 STE7

    Mass Spectrometry Data

    The following runs contain data for this protein:

      BAIT COMMENTS PUBLICATION
    View Run MLP2 #24 Asynchronous Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)
    View Run MLP2 #06 Alpha Factor Prep3-TiO2 Phosphopeptide enrichment Keck JM, et al. (2011)

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

      PROTEIN(S) PUBLICATION
    View Data FUS3 Huh WK, et al. (2003)

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..62]
    [74..95]
    [333..353]    		 PSI-BLAST 1087.9794 MAP kinase Erk2
    2 View Details [63..73]
    [96..332]    		 PSI-BLAST 1087.9794 MAP kinase Erk2


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle