YRC Public Data Repository - Protein Structure Prediction

Protein:	FUS3
Organism:	Saccharomyces cerevisiae
Length:	353 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FUS3.

Description	E-value	Query Range	Subject Range
gi\|13620175 - gi\|13620175\|emb\|CAC36428.1\| mitogen activated protein kinase [Gibberella fujikuroi]	0.0	[3..352]	[13..354]
FUS3_YEAST - Mitogen-activated protein kinase FUS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=FU... gi\|151946379 - gi\|151946379\|gb\|EDN64601.1\| serine/threonine protein kinase [Saccharomyces cerevisiae YJM789] FUS3 - Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; sub...	0.0	[1..353]	[1..353]
gi\|12005890 - gi\|12005890\|gb\|AAG44657.1\|AF258529_1 MAP kinase 1 [Gaeumannomyces graminis]	0.0	[3..352]	[14..355]
MPK4_ARATH - Mitogen-activated protein kinase 4 OS=Arabidopsis thaliana GN=MPK4 PE=1 SV=2	0.0	[4..350]	[33..366]
gi\|32421451, gi\|... - gi\|32421451\|ref\|XP_331169.1\| hypothetical protein ( (AF348490) MAP kinase [Neurospora crassa] ), gi... gi\|85093539 - gi\|85093539\|ref\|XP_959713.1\| hypothetical protein ( (AF348490) MAP kinase [Neurospora crassa OR74A] ...	0.0	[3..352]	[10..351]
gi\|9858841 - gi\|9858841\|gb\|AAG01162.1\|AF286533_1 mitogen-activated protein kinase [Fusarium oxysporum f. sp. lyco... gi\|97973996 - gi\|97973996\|dbj\|BAE94378.1\| mitogen activated protein kinase [Fusarium sacchari]	0.0	[3..352]	[13..354]
gi\|12657601\|dbj\|... - mitogen-activated protein kinase [Glomerella cingulata] gi\|12657601 - gi\|12657601\|dbj\|BAB21569.1\| mitogen-activated protein kinase [Colletotrichum gloeosporioides]	0.0	[3..352]	[13..354]
gi\|5739482 - gi\|5739482\|gb\|AAD50496.1\|AF174649_1 mitogen activated protein kinase [Colletotrichum lagenarium]	0.0	[3..352]	[13..354]

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Predicted Domain #1

Region A:
Residues: [1-62]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKRIVYNIS SDFQLKSLLG EGAYGVVCSA THKPTGEIVA IKKIEPFDKP LFALRTLREI  60
   61 KI

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [74-95]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IFNIQRPDSF ENFNEVYIIQ EL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [333-353]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HYKEALTTKD LKKLIWNEIF S

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1087.9794
Match:	1erk__
Description:	MAP kinase Erk2
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [63-73]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKHFKHENII T

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [96-332]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTDLHRVIS TQMLSDDHIQ YFIYQTLRAV KVLHGSNVIH RDLKPSNLLI NSNCDLKVCD  60
   61 FGLARIIDES AADNSEPTGQ QSGMTEYVAT RWYRAPEVML TSAKYSRAMD VWSCGCILAE 120
  121 LFLRRPIFPG RDYRHQLLLI FGIIGTPHSD NDLRCIESPR AREYIKSLPM YPAAPLEKMF 180
  181 PRVNPKGIDL LQRMLVFDPA KRITAKEALE HPYLQTYHDP NDEPEGEPIP PSFFEFD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1087.9794
Match:	1erk__
Description:	MAP kinase Erk2
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits