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Protein Overview: ATS1

General Information:
Name(s) found: ATS1 / YAL020C [SGD]
Description(s) found:
Found 22 descriptions.
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  • Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle [SGD]
    • Organism: Saccharomyces cerevisiae
    Length: 333 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IPILink to PubMed article]
    Biological Process: microtubule cytoskeleton organization [IGILink to PubMed article][IMPLink to PubMed article]
    budding cell bud growth [IGILink to PubMed article][IMPLink to PubMed article]
    tRNA modification [IMPLink to PubMed article]
    microtubule-based process [IGILink to PubMed article][ISSLink to PubMed article]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSCVYAFGSN GQRQLGLGHD EDMDTPQRSV PGDDGAIVRK IACGGNHSVM LTNDGNLVGC  60
   61 GDNRRGELDS AQALRQVHDW RPVEVPAPVV DVACGWDTTV IVDADGRVWQ RGGGCYEFTQ 120
  121 QHVPLNSNDE RIAVYGCFQN FVVVQGTRVY GWGSNTKCQL QEPKSRSLKE PVLVYDTGSV 180
  181 AVDYVAMGKD FMVIVDEGGR IVHASGRLPT GFELKQQQKR HNLVVLCMWT SIHLWNARLN 240
  241 TVESFGRGTH SQLFPQERLD FPIVGVATGS EHGILTTANQ EGKSHCYNVY CWGWGEHGNC 300
  301 GPQKASQPGL QLVGQYSGKP RVFGGCATTW IVL

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Riffle et al. (2010) (Unpublished Data) ATS1 DPH1 DPH2 KTI11
    View Details Krogan NJ, et al. (2006) ATS1 KTI11

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..333] PSI-BLAST 96.0 Regulator of chromosome condensation RCC1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.79978015066238 bayes_pls_golite062009
  • Ran guanyl-nucleotide exchange factor activity
    		•  1.12611051197363 bayes_pls_golite062009
  • nucleoside-triphosphatase regulator activity
    		•  1.05993294531818 bayes_pls_golite062009
  • GTPase regulator activity
    		•  1.03758696380346 bayes_pls_golite062009
  • ligase activity
    		•  0.957134518791255 bayes_pls_golite062009
  • guanyl-nucleotide exchange factor activity
    		•  0.947267197207143 bayes_pls_golite062009
  • small GTPase regulator activity
    		•  0.882132361980766 bayes_pls_golite062009
  • protein binding
    		•  0.775788303004353 bayes_pls_golite062009
  • Ras guanyl-nucleotide exchange factor activity
    		•  0.642436223706285 bayes_pls_golite062009
  • catalytic activity
    		•  0.261970921089142 bayes_pls_golite062009


    Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle