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Protein Overview: gi|149025685, gi...

General Information:
Name(s) found: gi|38014563 [NCBI NR]
gi|149025685 [NCBI NR]
Description(s) found:
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  • gi|38014563|gb|AAH60575.1| Proteasome (prosome, macropain) subunit, alpha type 5 [Rattus norvegicus] [NCBI NR]
  • gi|149025685|gb|EDL81928.1| proteasome (prosome, macropain) subunit, alpha type 5, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • proteasome (prosome, macropain) subunit, alpha type 5 [Mus musculus]gi|23110942|ref|NP_002781.2| proteasome alpha 5 subunit [Homo sapiens]gi|53734656|gb|AAH83342.1| Proteasome (prosome, macropain) subunit, alpha type 5 [Mus musculus]gi|38014563|gb|AAH6 [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 Proteasome (Prosome, macropain) subunit, alpha type 5 [EBI-IPI_rat_3.13_12-01-2005_con_reversed.fasta]
  • proteasome (prosome, macropain) subunit, alpha type 5, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proteasome (prosome, macropain) subunit, alpha type 5 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Proteasome subunit alpha type OS=Rattus norvegicus GN=Psma5 [011711_HMR.fasta]
  • Proteasome subunit alpha type OS=Rattus norvegicus GN=Psma5 PE=2 SV=1 [UNIPROT_RAT_07-21-2011_reversed.fasta]
  • Isoform of P34064, Proteasome subunit alpha type OS=Rattus norvegicus GN=Psma5 PE=1 SV=1 [RAT.fasta.20160308]
    • Organism: Rattus norvegicus
    Length: 241 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IEA]
    cytoplasm [IEA]
    proteasome core complex, alpha-subunit complex [IEA]
    Biological Process: anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process [UNKNOWN]
    positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [UNKNOWN]
    proteolysis involved in cellular protein catabolic process [IEA]
    ubiquitin-dependent protein catabolic process [IEA]
    negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle [UNKNOWN]
    Molecular Function: protein binding [UNKNOWN]
    threonine-type endopeptidase activity [IEA]
    peptidase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLTRSEYDR GVNTFSPEGR LFQVEYAIEA IKLGSTAIGI QTSEGVCLAV EKRITSPLME  60
   61 PSSIEKIVEI DAHIGCAMSG LIADAKTLID KARVETQNHW FTYNETMTVE SVTQAVSNLA 120
  121 LQFGEEDADP GAMSRPFGVA LLFGGVDEKG PQLFHMDPSG TFVQCDARAI GSASEGAQSS 180
  181 LQEVYHKSMT LKEAIKSSLI ILKQVMEEKL NATNIELATV QPGQNFHMFT KEELEEVIKD 240
  241 I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..241] PSI-BLAST 71.0 Proteasome alpha subunit (non-catalytic)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • endopeptidase activity
    		•  6.91642761177919 bayes_pls_golite062009
  • peptidase activity
    		•  6.84511694091156 bayes_pls_golite062009
  • peptidase activity, acting on L-amino acid peptides
    		•  6.5973571808298 bayes_pls_golite062009
  • hydrolase activity
    		•  4.47652590304822 bayes_pls_golite062009
  • threonine-type endopeptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • threonine-type peptidase activity
    		•  2.98214579292788 bayes_pls_golite062009
  • catalytic activity
    		•  1.19663085909195 bayes_pls_golite062009
  • binding
    		•  0.982918122186083 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.448212653390607 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle